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Editor-in-Chief eMediNexus – Dr KK Aggarwal
9th June 2018
WHO Priority Diseases: Disease X

Dr KK Aggarwal, Recipient of Padma Shri

WHO has added a new, yet unknown disease, calling it ‘Disease X’, in its list of eight priority diseases, which pose a public health risk due to their epidemic potential and for which there are no drugs or vaccine to treat them or prevent them. And there is an urgent need for research into these diseases for better diagnostic methods, improved vaccines and treatment.

"Disease X represents the knowledge that a serious international epidemic could be caused by a pathogen currently unknown to cause human disease, and so the R&D Blueprint explicitly seeks to enable cross-cutting R&D preparedness that is also relevant for an unknown "Disease X" as far as possible,"says the WHO.

It is believed that the next big global epidemic could be even deadlier than the presently known diseases such as Ebola. Just as the pathogen is unknown, so is its probable source. But, it is presumed that it will most likely be a zoonotic disease, with animals as the source of infection. And, modern travel and transportation will only facilitate rapid spread of the infection so that it becomes a global threat. Mutations can change the existing viruses into genetically new virus types. Then lab-mutated viruses or creation of new viruses in labs can also be a likely source. We don’t know. These are only speculations...... read more


How can Electronic Health Records Improve your practice

Are you a medical practitioner, who dreams of expanding his practice, but the dreams get entangled with the daily operation of the practice? Does the doctor in you, has to take a back seat, to do the clerical tasks? Are you still stuck with physical paperwork? Electronic health records (EHR) is the answer to all your practice needs! With EHR, you can work hard and work smart.... read more

Top News

New WHO report reveals need for more humane, personalized approach for adults with intellectual and psychosocial disabilities

A new report "Mental health, human rights and standards of care" published by WHO Europe has shown a lack of awareness about mental health and human rights in the first place, even among staff including a lack of a humane, or personalized, approach. It’s an important concept in mental health, .... read more

Morning Medtalks

Morning MEDTalks with Dr KK Aggarwal 9th June 2018

Clinical: Can ageing be reversed: Ageing process will be 'reversible', according to two genetic engineers in just published book The Death of Death. Nanotechnology, turning 'bad' genes into healthy ones, eliminating dead cells from the body, repairing damaged cells, treatments with stem cells and 'printing' vital organs in 3D can work by lengthening the 'telomeres'. Telomeres become damaged and shortened with ... read more

Practice Updates

Blacks and Hispanics more likely to develop a second hemorrhagic stroke than whites

PBlack people were twice as likely to have another stroke and Hispanic people were 50% more likely to have another intracerebral hemorrhage than white people, according to a study published in the June 6, 2018 in the journal Neurology. .... read more

Adjuvant mFOLFIRINOX chemotherapy prolongs survival in patients with pancreatic cancer

According to a study presented at the 2018 ASCO meeting, adjuvant mFOLFIRINOX chemotherapy regimen in patients with surgically removed pancreatic cancer prolonged survival. Also, patients were cancer-free nine months longer than those who were treated with standard chemotherapy with gemcitabine. .... read more

Eosinophilic esophagitis linked to absence of SPINK7 in esophageal cells

Absence of SPINK7, a specific protein in cells lining the esophagus may cause inflammation and tissue damage in people with eosinophilic esophagitis, suggests a study published June 6, 2018 in the journal Science Translational Medicine. This protein was found in biopsies from healthy people. .... read more

Complete biochemical response seen with bezafibrate + UDCA treatment in primary biliary cholangitis

AAmong patients with primary biliary cholangitis who had had an inadequate response to ursodeoxycholic acid (UDCA) monotherapy, treatment with bezafibrate in addition to UDCA resulted in a rate of complete biochemical response that was significantly higher than the rate with placebo and UDCA therapy, concluded a study published June 7, 2018 in New England Journal of Medicine. Normal levels of alkaline phosphatase were observed in 67% of ..... read more

Study links vitamin D deficiency to peripheral arterial disease

A meta-analysis of literature studies published in the June 2018 issue of the Journal of Clinical Endocrinology & Metabolism has shown a significant association of vitamin D deficiency and vitamin D insufficiency with peripheral arterial disease (PAD) suggesting low vitamin D levels as a risk factor for PAD.... read more

Higher successful perfusion rates with mechanical thrombectomy followed by carotid stenting

As per a study presented at the 4th European Stroke Organisation Conference (ESOC) 2018 in Gothenburg, Sweden, adopting a retrograde approach (thrombectomy followed by stenting) in acute ischemic stroke patients presenting with a tandem occlusion, resulted in 92% successful perfusion rate compared to antegrade approach, when the outcome was a 56% perfusion rate..... read more

eMedi Humor
Medicolegal Corner
eMedi Quiz
1. Glyceraldehyde-3-phosphate dehydrogenase.
2. Phosphoglucomutase.
3. Lactate-dehydrogenase.
4. Glucokinase.
Lifestyle Updates
Inspirational Story 2: The Father and His Sons
Maternal mortality down in India; still a long way to go
Anemia among the major causes for death in mothers
New Delhi, 8 June 2018: In India, more women are now delivering babies in hospitals, which has brought down the number of women dying during childbirth in the country. As per recently released data by the office of the Registrar General of India, the maternal mortality rate (MMR) declined to 130 in 2014/16 from 167 in 2011/13.

MMR is defined as the number of maternal deaths per 100,000 live births. The causes range from excessive blood loss (post-partum hemorrhage) to infections, primarily because women do not give birth in a hospital or health centre. The major cause, post-partum hemorrhage is usually defined as the loss of more than 500-1,000 ml of blood within the first 24 hours following childbirth.

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