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Dr k k Aggarwal Special

CMAAO Coronavirus Facts and Myth Buster: Anaphylaxis; Autoantibodies

Dr KK Aggarwal President CMAAO, HCFI
7th February 2021
With input from Dr Monica Vasudev
1346: Anaphylaxis
1. 21 cases of anaphylaxis out of 1.8 M doses of Pfizer-BioNTech vaccine – approximately 1 in 87,000 injections). Although this is rare, but it is higher than the risk with other vaccines which is 1.3 per million. 2. Majority of anaphylaxis cases have been reported within 30 minutes of receiving the jab. 3. Of 21 cases, 5 were allergic to some food; three of these also had a history of drug allergy. Twelve had had allergic reactions to medications or vaccines previously, and one had environmental allergies. 4. Moderna vaccine - some cases of delayed facial swelling have been reported without serious consequences. 5. Vaccine allergy is a rare occurrence. The cause behind such rare allergic reactions is often an excipient... Read more »
Dr k k Aggarwal

World COVID Meter 6th February 2021: Acute manageable immunogenic thrombogenic inflammatory contagious viral disease pandemic

Dr KK Aggarwal, President CMAAO, HCFI and Past National President IMA
7th February 2021
Cases: 1M April 2, 2M April 15, 3M April 27, 4M May 8, 5M May 20, 6M May 30, 7M June 7, 8M June 15, 9M June 22, 10M June 29th, 11M July 4, 12M July 8, 13M July 13, 14M July 17, 15M July 23, 16M July 25, 17M July 29, 18M August 1, 19M August 6, 20M August 10, 21M August 16, 22M August 19, 23M August 21, 24M August 27, 25M August 30, 26M September 3, 27M September 7, 28M September 10, 29M September 14, 30M September 18, 31M September 21, 32M September 23, 33M September 28, 34M October 1, 35M October 4, 36M October 8, 37M October 11, 38M October 14, 39M October 17, 40M October 19, 41M October 22, 42M October 24, 43M October 26, 44M October 28,... Read more »
Dr k k Aggarwal

Reproductive Considerations in Liver Disease in women

7th February 2021 Gastroenterology Hepatology Multispeciality
Women are at risk of acute and chronic liver diseases and the diseases affecting pregnant women with adverse effects on maternal, fetal, or neonatal outcomes are of utmost importance. Among these diseases, acute viral hepatitis is a crucial cause of liver disease in pregnant women, and hepatitis E... Read more »
Cough Update

Effectiveness and safety of ambroxol for the treatment of symptoms of acute and chronic respiratory diseases, especially in children

7th February 2021 Allergy & Immunology Multispeciality
Ambroxol (2-amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine), an over-the-counter mucoactive agent has been successfully used to treat both acute and chronic respiratory diseases since 1978. The current review is aimed to establish clinical evidences on its use in children with acute and chronic respiratory diseases.... Read more »

News From All Specialities

WHO revises critical concentrations for susceptibility testing to rifampicin

7th February 2021 Business and Medicine Pathology & Lab Medicine
The World Health Organization (WHO) has updated the critical concentrations for culture-based phenotypic drug susceptibility testing (DST) to anti-tuberculosis drugs. The agency has reduced the critical concentrations for rifampicin; however, that for isoniazid continues to be at the current level... Read more »

FDA Approves Cell-based Gene Therapy for Adults with Relapsed or Refractory Large-B-Cell Lymphoma

7th February 2021 Business and Medicine Pathology & Lab Medicine
The U.S. Food and Drug Administration has granted approval to lisocabtagene maraleucel, for the treatment of adult patients with some forms of large B-cell lymphoma who either do not respond to, or have relapsed, following at least two systemic treatments with other agents. This drug is a chimeric antigen receptor (CAR) T cell therapy... Read more »

New Zealand probes new COVID-19 case tied to quarantine facility

7th February 2021 Pathology & Lab Medicine Pulmonary Medicine
Health authorities in New Zealand are probing a new community COVID-19 infection, which is the fourth in a two weeks’ span in people who have completed the compulsory isolation at a quarantine facility for those who have returned from overseas. The new case has been detected in an individual who was self-isolating at home in Hamilton,... Read more »

COVID-19 vaccination for citizens above 50 to start in March, says Health Minister

7th February 2021 Pathology & Lab Medicine Pharmacists
The third phase of inoculations against COVID-19, which includes citizens over 50 years of age and those who are younger than 50 but have serious co-morbidities, will start probably around mid-March, stated health minister Dr Harsh Vardhan in the Lok Sabha. The government had recently suggested that the individuals above 50 years... Read more »

Anti-CD20 Drugs Associated with Severe COVID-19 in Cancer Patients

7th February 2021 Pharmacists Pathology & Lab Medicine
Findings presented at the American Association for Cancer Research (AACR) COVID-19 and Cancer meeting have suggested that drugs targeting CD20, such as rituximab and obinutuzumab, were associated with severe COVID-19 disease in patients with lymphoma. Researchers noted that among more than 100 lymphoma patients... Read more »

Medicolegal Corner

Some situations of negligence as defined by the Supreme Court of India

7th February 2021
In Martin F. D’Souza vs Mohd. Ishfaq, 3541 of 2002, dated 17.02.2009, the Supreme Court has defined some situations of negligence as follows:
1. Failure to strictly observe current practices, infrastructure, paramedical and other staff, hygiene and sterility... Read more »

eMedi Humor

My Grades

7th February 2021
A high–school student came home one night rather depressed.
"What’s the matter, Son?" asked his mother.
"Aw, gee," said the boy, "It’s my grades. They’re all wet." ... Read more »

eMedi Quiz

The cells belonging to the following type of epithelium are provided with extra reserve of cell membrane:

7th February 2021
1. Transitional
2. Stratified squamous
3. Stratified cuboidal... Read more »

Lifestyle Updates

eWellness: Eating Out Tips

7th February 2021
• Restrain on portion size: Order for one if you are two people; if you are alone, set aside some of the food on your plate to bring home.
• Resist refined carbohydrates.
• Fill your plate with colorful choices with vegetables, fruits and small amounts of lean protein. Avoid creamy and ranch dressings... Read more »

eSpiritual: Importance of silence

7th February 2021
True silence is the silence between thoughts and represents the true self, consciousness or the soul. It is a web of energized information ready to take all, provided there is a right intent. Meditation is the process of achieving this silence. Observing silence is another way of getting benefits of meditation... Read more »

Inspirational: Benefits of Struggling

7th February 2021
A man once saw a cocoon of a butterfly in his garden. One day he noticed a small opening in the cocoon. He watched the butterfly for hours altogether as it struggled to come out through the hole. Eventually, it appeared that it had stopped making any progress. The man thought of helping the butterfly. He brought a pair of scissors and cut the remaining part of the cocoon... Read more »

Medical Voice

Is it safe to take painkillers before or after getting vaccinated for coronavirus?

7th February 2021
Can I take painkillers before or after a Covid-19 vaccine? It's best to avoid them, unless you routinely take them for a medical condition. Although the evidence is limited, some painkillers might interfere with the very thing the vaccine is trying to do: generate a strong immune system response... Read more »


Medical voice

Doctors Survey

Question 1 : Which of these courses would you pay for - You can select multiple options
How to modernize clinic
Growing your digitize you clinic and practice...
Medical voice

How Corona Aware Are You

Question 1 : How confident are you that you could recognize and respond to a potential coronavirus case?
Very confident
Moderately confident...


From Other Newsletter

Recovery Digest


Oral Rehydration Therapy in Thoracic Surgery

The goal of a study published in Kyobu Geka was to evaluate safety and efficacy of preoperative oral rehydration therapy compared to infusion therapy in thoracic surgery. In this study, 84 patients scheduled for thoracic surgery were assigned to either an oral rehydration group or an infusion group... Read more »



Ambulatory blood pressure monitoring in patients with essential hypertension treated with cilnidipine

In the present study, published in Cardiovascular Drugs and Therapy, cilnidipine was given to 14 hospitalized patients with essential hypertension, and 24-hour ambulatory BP monitoring was performed. Once-daily administration of cilnidipine... Read more »


Effect of Baby Swimming and Baby Lotion on the Skin Barrier of Infants Aged 3-6 Months

Skin care is important especially in infancy as skin barrier matures during the first year of life. The goal of a study published in Journal of the German Society of Dermatology was to examine the effects of baby swimming and baby lotion... Read more »


An antibiofilm hydrofiber wound dressing: Clinical and in vitro performance

Biofilm has often been cited as a key pathological factor in non-healing wounds. It therefore seems crucial to manage the biofilm in order to expedite wound healing and achieve the desired outcome. A study by Scully and colleagues compared the clinical and in vitro performance of a next-generation antibiofilm silver dressing (NGAD) enriched with an antimicrobial dressing technology... Read more »

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