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Editorial (Dr SS Agarwal, Dr K K Aggarwal)
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6th September 2016
Beware of Chikungunya encephalitis: IMA
Chikungunya virus (CHIKV) disease can cause CHIKV-associated encephalitis. CHIKV RNA or anti-CHIKV immunoglobulin M can be detected in the cerebrospinal fluid.
In a U-shaped distribution, children younger than 1 year and adults age 65 or older have the highest incidence of CHIKV-associated encephalitis as reported in a previous study. The overall case fatality rate for CHIKV-associated encephalitis is 16.6%, and the 3-year rate of neurologic sequelae range from 30% to 45%. The risk for death or neurologic sequelae is significantly higher in adults than in children (53% vs 18%).
CHIKV is an alphavirus transmitted by Aedes species mosquitoes. Symptomatic CHIKV infection typically results in a self-limited systemic febrile illness associated with rash and arthralgia. However, cases of severe disease, including meningoencephalitis and death, have also been reported.
CHIKV may have similar presentation as many other infectious causes of systemic febrile illness in the tropics, including malaria, dengue and other arthropod-borne infections.
Central India Institute of Medical Sciences, Nagpur in May 2006 described various neurological syndromes: Encephalitis, myelopathy, peripheral neuropathy, myeloneuropathy and myopathy, during a large CHIKV infection outbreak.
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Press Release
Beware of Chikungunya Encephalitis: IMA

New Delhi, September 05, 2016: Severe encephalitis related to chikungunya infection has been reported in Delhi said Padma Shri Awardee Dr K K Aggarwal National President Elect IMA.
Chikungunya virus (CHIKV) disease can cause CHIKV-associated encephalitis. One can detect CHIKV RNA or anti-CHIKV immunoglobulin M in cerebrospinal fluid, warns IMA. 
IMA was the first to report chikungunya cases in West Kidwai Nagar in NBCC construction area and is now first to report spurt of cases of encephalitis in Delhi linked to chikungunya, said Dr Aggarwal.
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