Preventive antibiotics said to have modest effect for recurrent UTIs.
Children who are predisposed to recurrent urinary tract infections are commonly treated with preventive antibiotics, and a new Australian study suggests that such prophylactic therapy may have at least a modest effect.In the study, appearing in the Oct. 29 issue of the New England Journal of Medicine, researchers found that only 13 percent of youngsters who were given the antibiotic combination of trimethoprim plus sulfamethoxazole developed a urinary tract infection while on the medication, compared to 19 percent of the children on a placebo.
Sliding Scale Vs Tight Glycemic Control in the Non critically Ill pts
Development of hyperglycemia during hospitalization is an area of concern in patients with and without diabetes. Tight glycemic control has been debated for critically ill and non critically ill patients with hyperglycemia. To compare traditional sliding scale (SS) with a tight glycemic control (TC) algorithm a study was done. The primary endpoint was the percentage of total blood glucose measurements in the target range of 80-150 mg/dL. The secondary endpoint evaluated was safety, defined as percentage of all blood glucose measurements that were 0-60 mg/dL. A cohort of patients managed with SS (n 121) was compared with those treated with TC (n 210). In the TC cohort, 42.9% of blood glucose measurements were in the target range of 80-150 mg/dL compared with 30.6% of the measurements in the SS cohort (p<0.001). Regarding safety, 2% of blood glucose measurements of the TC cohort were in the range of 0-60 mg/dL versus 0.3% of the SS cohort (p<0.001). No clinical sequelae of hypoglycemia were observed. Patients achieved more blood glucose measurements in the target range when treated with TC versus SS insulin, without regard to prior history of diabetes. The study concluded that patients treated with tight control experienced more blood glucose measurements in the target range as compared with patients treated with sliding scale with relatively low hypoglycemia rates. [Source Annals of Pharmacotherapy Oct 2009]
Thought for the day
To recognize the uniqueness of one's own role is to be free from negativity. When we find things going wrong with us, we sometimes wish for a change in our role. We begin to compare ourselves with others or wish for something better in our life, which makes us lose all our enthusiasm. We then make no effort to better our role. We need to recognise the importance of our own role. Like an actor who doesn't make effort to change his role but brings perfection to his own role, we, too, need to concentrate on our own role. The recognition of the importance of our own role and the desire to bring excellence to it makes us free from negativity. ( BK Sapna)
A man speaks frantically into the phone, My wife is pregnant, and her contractions are only two minutes apart.
Is this her first child? the doctor queries.
No, No: the man shouts. This is her husband.
Mistake of the day
Never write 2.0 mg, write 2 mg. As 2.0 may be misread as 20 mg.
Bedside Tip: a new approach to percussion
We have been taught the traditional technique of percussion: strike the terminal phalanx of the middle finger of the non dominant hand with the tip of the middle finger of the dominant hand. Try striking the non dominant middle finger with a reflex hammer. It is easier to perform, is more easily reproduced, provides more audible notes (especially important in a noisy setting such as the emergency department), and is less painful to the struck phalanx. Doctors with long fingernails will most appreciate this fact. (Dr Anil Malhotra Rajisthan)
Exposure to whooping cough may provide immunity for three decades
Exposure to whooping cough will provide immunity for an average of three decades, according to a study published in PLoS Pathogens.
The study revealed that immunity after natural infection lasts for at least three decades, on average, and maybe even as long as 70 years.
Furthermore, people who lose some of their immunity might still have some protection and even gain more immunity when they are exposed again to whopping cough.
Researchers say MRSA strain may be partially immune to treatment.
According to research scheduled to be presented at the annual meeting of the Infectious Diseases Society of America, a strain of methicillin-resistant Staphylococcus aureus (MRSA) that infects the bloodstream is five times more deadly than other strains.
Ultrasound of axillary lymph nodes before breast cancer surgery
Ultrasound combined with fine-needle aspiration for confirmation of metastases, could spare many early-stage patients from sentinel node biopsy and reoperation. This strategy picked up 29.8% of macrometastases in women scheduled for lumpectomy, with an overall accuracy of 84.4%, Bedanta Baruah, MD, of Cardiff University in Cardiff, U.K., and colleagues reported at the ASCO Breast Cancer Symposium.
Revisiting 2009, 10th January, MAMC Delhi, firstname.lastname@example.org
Advertising in emedinews
emedinews is a new venture of IJCP Group and is the first daily emedical newspaper of the country. One can advertise with a singe insertion or 30 insertions in a month. For details contact email@example.com.
emedinews: revisiting 2009
IJCP Group is organizing emedinews: Revisiting 2009, a day-long medical conference on 10th January, 2010 at Maulana Azad Auditorium. It will be attended by over 1000 doctors. Topics will be top happenings in the year 2009. There will be no registration fee. Advanced registration required. Top experts will deliver lectures. It will be followed with lively cultural evening, doctors of the year award, dance and dinner. For regiatration mail firstname.lastname@example.org
If one doctor doctors another doctor does the doctor who doctors the doctor doctor the doctor the way the doctor is doctoring doctors or does the doctor doctor the doctor the way that doctor doctors doctors.