Avoid concomitant use of fluoroquinolones with corticosteroids as much as possible: Monitor your patient for signs of tendon injury
The broad-spectrum fluoroquinolone antibiotics are used to treat common infections such as respiratory tract infections, urinary tract infections. However, their use is associated with serious adverse events regarding which the US FDA has issued safety communications.
In July 2008, the FDA mandated the first black box warning for fluoroquinolone antibiotics for increased risk of tendinitis and tendon rupture. Since then, other black box warnings have been issued: August 2013 (peripheral neuropathy), May 2016 (restricting use for certain uncomplicated infections), July 2016 (disabling side effects) and the most recent being in July 2018 (hypoglycemia and mental health side effects including disturbances in attention, disorientation, agitation, nervousness, memory impairment and delirium)...read more
The Confederation of All India Traders (CAIT) has written to the Finance Minister Arun Jaitley on Sunday seeking investigation to assess the potential of health hazards allegedly posed by currency notes and urged him to take preventive measures to protect people from diseases due to their contamination.... read more
The Health Ministry released the draft of a "charter of patient rights" prepared by National Human Rights Commission (NHRC). The draft is in public domain for comments and suggestions for a period of 30 days. The ministry plans to implement the charter through state governments for provision of proper health care to patients by clinical establishments. The charter includes 17 rights of patients (as follows) along with the description of the rights and duty bearers... read more
As per a study of inpatient systemic sclerosis (SSc) hospitalizations, infections are currently the most common diagnoses among hospitalizations systemic sclerosis and in-hospital deaths in patients with SSc. The study published in the September 2018 issue of the journal... read more
A cost-effectiveness analysis comparing pharmacotherapy with surgery as initial therapy for patients with moderate-to-severe benign prostate hyperplasia (BPH) has found surgery to be more cost-effective as initial therapy for moderate-to... read more
The US Food and Drug Administration (FDA) has rejected the new drug application (NDA) for dasotraline (Sunovion Pharmaceuticals), a novel dual-acting dopamine and norepinephrine reuptake inhibitor, for the treatment of attention-deficit/hyperactivity disorder (ADHD)... read more
Children need to limit their use of smartphone and screen time on other devices and so do parents, says a report published August 27, 2018 in JAMA Pediatrics. Children learn smartphone habits from their parents; hence, “The more we parents demonstrate this type of tech-life balance,... read more
A new observational study published in the September 2018 issue of the journal Pediatrics concluded that short children with low mid-upper arm circumference do not gain excessive fat during supplementation. The authors of the study recommend a policy change to include all.. read more
Leptospirosis cases spiral in flood-affected Kerala Preventive care and precautions are the only ways to prevent this condition
New Delhi, 03 September 2018: Flood-hit Kerala reported yet another rat fever victim recently. Also known as leptospirosis, the disease has already claimed 15 lives so far and about 40 cases have been reported in the beginning of September. With two million people in the state having come into contact with flood waters, the need of the hour is to stress on preventive care.
Leptospirosis is a potential zoonosis with protean manifestations, caused by pathogenic spirochetes of the genus Leptospira. The organism infects a variety of wild and domestic mammals, especially rodents, cattle, swine, dogs, horses, sheep, and goats. Reservoir animals shed the organism in their urine intermittently or continuously throughout life, resulting in contamination of water.