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Dr k k Aggarwal Special

CMAAO Coronavirus Facts and Myth Buster: HCQ

Dr K K Aggarwal, President CMAAO
4th October 2020
With input from Dr Monica Vasudev
1099: HCQ Fails as COVID-19 Pre-Exposure Prophylaxis for HCPs
1. There appeared to be no clinical benefit to hydroxychloroquine (HCQ) as COVID-19 pre-exposure prophylaxis in a small sample of healthcare professionals in a randomized trial that was stopped early owing to futility. 2. Participants given daily HCQ for 8 weeks reported no significant difference in infection rates compared to those randomized to placebo therapy (6.3% vs 6.6%, respectively, P >0.99). 3. The median change in QTc baseline was not different; however, overall adverse events appeared to be significantly more common in the HCQ group than the placebo group, noted the authors in JAMA Internal Medicine. ...Read more »
Dr k k Aggarwal

World COVID Meter 3rd October: Acute manageable immunogenic thrombogenic inflammatory viral disease pandemic

Dr KK Aggarwal, President CMAAO, HCFI and Past National President IMA
4th October 2020
Cases:: 1M April 2, 2M April 15, 3M April 27, 4M May 8, 5M May 20, 6M May 30, 7M June 7, 8M June 15, 9M June 22, 10M June 29th, 11M July 4, 12M July 8, 13M July 13, 14M July 17, 15M July 23, 16M July 25, 17M July 29, 18M August 1, 19M August 6, 20M August 10, 21M August 16, 22M August 19, 23M August 21, 24M August 27, 25M August 30, 26M September 3, 27M September 7, 28M September 10, 29M September 14, 30M September 18, 31M September 21, 32M September 23, 33M September 28, 34M October 1. Ground Zero: Wuhan - in live animal market or cafeteria for animal pathogens: 10th January; Total cases are based on RT PCR, 67% sensitivity. Coronavirus Cases: 34,823,216, Deaths: 1,033,174 Recovered: 25,889,974,... Read more »
Dr k k Aggarwal

Pharmacokinetics in Older Adults

4th October 2020Gastroenterology Hepatology Multispeciality
An article published in MSD Manual defined pharmacokinetics as ‘what the body does to the drug’ – involving absorption; distribution across body compartments; metabolism; and excretion. The authors stated that with aging, there are changes in all these areas, while some changes are more clinically relevant... Read more »

Hypertension Update

Dr k k Aggarwal

Efficacy of Combination Therapy with Amlodipine & ARBs in Asian Hypertensive Patients

4th October 2020 Hypertension
Hypertension (HTN) is a major risk factor for cardiovascular mortality across the globe. There are several studies that have compared the safety and efficacy between different antihypertensive classes;... Read more »
Zinc Update

Zinc and Sepsis

4th October 2020Allergy & Immunology Multispeciality
An article published in the journal Nutrients defined sepsis as a “life-threatening organ dysfunction caused by a dysregulated host-response to infection”. The authors discussed that sepsis is a major health issue across the world; however, there is still a lack of clearly explained pathobiology and uniform diagnostic tests... Read more »

News From All Specialities

World leaders, celebrities to join WHO’s Event for Mental Health

4th October 2020 Business and Medicine Pathology & Lab Medicine
World leaders and internationally-recognized celebrities and mental health advocates intend to come together for the World Health Organization’s Big Event for Mental Health on October 10, World Mental Health Day. WHO’s first-ever online advocacy event for mental health is focused on the urgent need to address... Read more »
Practice Updates

COVID-19 vaccine roll-out expected in Britain in less than 3 months: The Times

4th October 2020 Pathology & Lab Medicine Pulmonary Medicine
A mass roll-out of a COVID-19 vaccine in the UK could be finished within three months’ time, reported the Times, while citing government scientists. The newspaper stated that scientists working on the Oxford vaccine are hopeful that the regulators will approve it before the beginning of 2021... Read more »

Drug Combination for Treating Mesothelioma Receives FDA Approval

4th October 2020 Pathology & Lab Medicine Pulmonary Medicine
The U.S. Food and Drug Administration has granted approval to nivolumab, in combination with ipilimumab, for the first-line treatment of adults with malignant pleural mesothelioma, which cannot be removed surgically. This is the first drug regimen that has been granted approval for mesothelioma in 16 years’ time...Read more »

COVID-19: Reliance develops RT-PCR kit that can give results in 2 hours

4th October 2020 Pharmacists Emergency Medicine
New Delhi: Reliance Life Sciences has developed an RT-PCR kit to test for COVID-19 that may provide results in about 2 hours, stated company sources. Presently, COVID-19 RT-PCR test, a real-time reverse transcription-polymerase chain reaction (rRT-PCR) test, used for the qualitative detection of nucleic acid from SARS-CoV-2,...Read more »

Menopausal Symptoms Linked with Cardiovascular Risk

4th October 2020 Cardiology Pharmacists
Analysis of data from the Women's Health Initiative CaD (Calcium and Vitamin D) trial has revealed that women with greater menopausal symptoms experienced higher risk of cardiovascular illness. Women having two or more moderate to severe menopausal symptoms were found to have higher... Read more »

Medicolegal Corner

If the doctor waives off his fees, will he still be held liable for medical negligence?

4th October 2020
Waiving off fee does not take away the responsibility of the doctor. If the doctor has not charged his fees but has committed medical negligence or does not treat his patient properly, then also the doctor shall be liable to pay compensation to the patient and/or patient’s relatives for the same....Read more »

eMedi Humor


4th October 2020
A guy approached a beautiful looking woman in a mall and asked, "You know, I’ve lost my wife here in the mall. Can you talk to me for a couple of minutes?"
"Why?" she asks. ...Read more »

eMedi Quiz

Elements of primary health care include all of the following except:

4th October 2020
1. Adequate supply of safe water and basic sanitation.
2. Providing essential drugs.
3. Sound referral system...Read more »

Lifestyle Updates

eWellness: Clinicians should aggressively treat unhealthy lifestyles

4th October 2020
Unhealthy behaviors should be managed as aggressively as hypertension, high cholesterol, and other heart disease risk factors, according to an American Heart Association policy statement published in the journal Circulation. Doctors should create "interprofessional practices" to connect patients with behavior-change specialists... Read more »

eSpiritual: Why do We Burn Camphor in Any Pooja?

4th October 2020
No Aarti is performed without camphor. Camphor burns itself out completely when it is lit, without leaving a trace. Camphor represents our inherent tendencies or vasanas. When lit by the fire of knowledge about the self, the vasanas burn themselves out completely, not leaving a trace of ego...Read more »

Inspirational: Hitting Unseen Target

4th October 2020
Yogi Raman was a master of the art of archery. One morning, he asked his favorite disciple to witness a display of his skill. The disciple had seen this over a hundred times before, but he obeyed. They went into the woods and when they reached a beautiful oak tree,...Read more »

Medical Voice

Those under 40 are paying the price for taking Covid-19 lightly

4th October 2020
A 40-year-old man from Andheri West has been fighting for his life since he was admitted to the intensive care unit at Lilavati Hospital on September 27 with Covid-19. He told doctors that he’d had a fever on and off since September 16 and had been taking antibiotics without consulting a doctor...Read more »


Medical voice

Doctors Survey

Question 1 : Which of these courses would you pay for - You can select multiple options
How to modernize clinic
Growing your digitize you clinic and practice...
Medical voice

How Corona Aware Are You

Question 1 : How confident are you that you could recognize and respond to a potential coronavirus case?
Very confident
Moderately confident...


From Other Newsletter


Vitamin A intake linked with lower skin cancer risk: Study

Intake of vitamin A may be associated with a lower risk of a common type of skin cancer, a study claims. The study of about 125,000 Americans found that people with the highest intake of vitamin A lowered their risk of squamous cell skin cancer by around 15 per cent.... Read more »



Blood pressure control with cilnidipine treatment in Japanese post-stroke hypertensive patients

Calcium channel blockers (CCBs) are the choice of therapy for post-stroke patients. A large-scale prospective study of 2667 post-stroke hypertensive patients treated with cilnidipine assessed BP control and adverse reactions in the patients... Read more »



How does sleep duration affect the development of osteoporosis

The American National Sleep Foundation recommends 7-9 hours of sleep per day for adults 18 years of age and older. There has been increasing amount of research into the association between osteoporosis and sleep. Longer sleep duration has been tied to increased risk of osteoporosis.... Read more »


Understanding how skin barrier evolves and reacts during the first few years of life

The structure of the stratum corneum (SC) and corresponding skin barrier develops from before birth up to about 4 years of age. Understanding the evolution of skin barrier structure during the first few years of life is the first step to developing solutions for improved infant skin health... Read more »


Bariatric surgery prevents severe CKD and ESRD

Patients that underwent weight-loss surgery lowered their risk of developing severe chronic kidney disease (CKD) and end stage renal disease (ESRD) when compared to conventionally treated patients, according to a study published in International Journal of Obesity... Read more »

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