Editor-in-Chief eMediNexus – Dr KK Aggarwal
31st January 2019
Anger management: An anger episode may trigger an acute heart attack within 2 hours

Dr KK Aggarwal, Padma Shri Awardee

Emotionally stressful events, and more specifically, anger, immediately precede and appear to trigger the onset of acute myocardial infarction (MI) and other cardiovascular events.

Outbursts of anger increase the risk of acute myocardial infarction, acute coronary syndrome, ischemic stroke, ruptured intracranial aneurysm and ventricular arrhythmia. This was corroborated by a systematic review and meta-analysis published in the European Heart Journal, which found a higher risk of cardiovascular events in the 2h after outbursts of anger (Eur Heart J. 2014 Jun 1;35(21):1404-10)...read more

Four trials published in 2018 that may shape neurology practice

Dr KK Aggarwal, Padma Shri Awardee

A new treatment option for brain metastases: The usual survival period after brain metastases is 2-4 months. Brain metastasis generally means palliative care. In a study published online August 2018 in the New England Journal of Medicine (N Engl J Med. 2018;379:722-730), nivolumab combined with ipilimumab had clinically meaningful intracranial efficacy, concordant with extracranial activity, in patients with melanoma who had asymptomatic untreated brain metastases. Benefit in intracranial growth of metastases was seen in 57% of patients, 64% of patients did not show any progression of the disease, and the 6-month survival was 80%...read more

Practice Updates

Manufacturer to pay penalty for entire batch if single drug found substandard

Even if a single drug in a batch is found substandard the manufacturer may have to pay a penalty equal to the MRP of the entire batch shipped, according to a new government proposal. There are usually 10,00 to one lakh units in a batch, but the number of drugs - which can be in the form of tablets or liquid - in a batch vary depending on the size of the shipment, a Health... read more

FSSAI bans use of staple pins in tea bags

In an order dated 25th Jan. 2019, the FSSAI has banned the use of staple pins in tea bags. Vide order No. 1-95/Stds/Misc/SP(L&C/A)/FSSAI-2015 dated 18.7.2017 and 15.11.17 has directed... read more

Cabo Verde leads the way in ending new HIV infections in children in West and Central Africa

Cabo Verde has prioritized the elimination of HIV transmission from mother to child because, as Minister of Health Arlindo Nascimento do Rosario says emphatically, "Every child has a right to be born healthy and to live a healthy life. They are born to shine"... read more

Intensive control of BP reduces mild cognitive impairment

Intensive lowering of blood pressure did not significantly reduce dementia risk but did have a measurable impact on mild cognitive impairment (MCI), according to the final, peer-reviewed results from the Systolic Blood Pressure Intervention Trial (SPRINT) Memory and Cognition in...read more

NICE draft guidelines recommend digital CBT for mild depression in children

The National Institute for Health and Care Excellence (NICE) has published draft guidelines for identification and management of depression in children. It recommends digital cognitive behavioral therapy (digital CBT) on mobile phones, tablets, and computers for mild depression... read more

Antibiotic treatment prolongs hospitalization for asthma patients

Compared with patients who were not treated with antibiotics, treatment with antibiotics during hospitalization for asthma exacerbation was associated with longer hospital stays, similar rate of treatment failure, higher risk of antibiotic-related dirrhea and higher hospital costs in a ... read more

eMedi Humor
Medicolegal Corner
eMedi Quiz
1. Vaginal bleeding is a warning sign for possible endometrial cancer or pathology in postmenopausal women on tamoxifen.
2. Fluoxetine is the "selective serotonin reuptake inhibitors (SSRI)" of choice for the management of hot flushes in women taking tamoxifen.
3. Estrogen replacement therapy is contraindicated in women with ER/PR positive breast cancer for managing hot flushes and bone loss.
4. Gabapentin is an active agent for the management of tamoxifen related hot flushes.
Lifestyle Updates
Inspirational Story 1: Always Remember Those Who Serve
Inspirational Story 2:Temper Control
India needs more awareness generation and removal of stigma around HIV/AIDS
Mother-to-child transmission of the disease can only be prevented through targeted efforts
New Delhi, 30 January 2019: About 80 adolescents will be dying of AIDS every day globally by 2030 if progress in preventing transmission is not accelerated, according to a report by the UNICEF. The report mentions that the current trends indicate that AIDS-related deaths and new infections are slowing, but the downward trajectory is not happening fast enough. Programmes to treat the virus and prevent it from spreading among older children are nowhere near where they should be.

Currently, three million persons 19 years and younger, are infected with HIV worldwide. Two million new infections could be averted by 2030, if global targets are met — this means providing adequate access to HIV prevention, care and treatment services, and testing and diagnosis.

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