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Editor-in-Chief eMediNexus – Dr KK Aggarwal
 
2nd December 2018
Updated ACIP recommendations for prevention of hepatitis A infection

Dr KK Aggarwal, Padma Shri Awardee

The United States Advisory Committee on Immunization Practices (ACIP) has issued updated recommendations for prevention of hepatitis A virus (HAV) infection in November 2018. Published in the Morbidity and Mortality Weekly Report, the ACIP says that postexposure prophylaxis (PEP) with hepatitis A (HepA) vaccine or immune globulin (IG) prevents infection with hepatitis A virus when administered within 2 weeks of exposure.

As per the guidelines, hepatitis A vaccine for postexposure prophylaxis provides advantages over IG, including induction of active immunity, longer duration of protection, ease of administration and greater acceptability and availability.

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Top News

Measles cases spike globally due to gaps in vaccination coverage

Reported measles cases spiked in 2017, as multiple countries experienced severe and protracted outbreaks of the disease, according to a new report jointly “Progress Toward Regional Measles Elimination - Worldwide, 2000-2017” published by the WHO and CDC. Because of gaps in vaccination coverage, measles outbreaks occurred in all regions, while there were an estimated ... read more

80 adolescents a day will still die of AIDS by 2030, despite slowdown in epidemic

In a report released on Thursday, Children, HIV and AIDS: The World in 2030, current trends indicate AIDS-related deaths and new infections are slowing, but the downward trajectory is not happening fast enough. By 2030, around 80 adolescents will be dying of AIDS every day if “we ... read more

Do You Know?

By the time you reach your 50th birthday, you've probably also reached another milestone: you've put 75,000 miles on your feet. You may reach this milestone much earlier if you've led a foot-active lifestyle. By age 50, you may have lost nearly half of the fatty padding on the soles of your feet. And you may be wearing a shoe that's a size bigger than what you wore in your 20s, in part ... read more

Morning Medtalks

Morning MEDtalks with Dr KK Aggarwal 2nd December 2018

Thirty years after the first World AIDS Day, the HIV response stands at a crossroads, UN Secretary-General António Guterres has said, marking this year’s commemorations. The direction taken now, may determine whether the epidemic can be ended by 2030, or if future generations will have to continue the battle, he said. In his message for the Day, which falls each 1 December, Mr. ... read more

Practice Updates

First test to aid in detecting cytomegalovirus in newborns

The US Food and Drug Administration (FDA) has permitted marketing of a new diagnostic test to aid in detecting a type of herpes virus called cytomegalovirus (CMV) in newborns less than 21 days of age. The Alethia CMV Assay Test System is used as an aid in the diagnosis of congenital ... read more


MRI with diffusion tensor imaging may predict risk of Alzheimer's dementia

A study from the Alzheimer's Disease Neuroimaging Initiative (ADNI) presented at the Radiological Society of North America annual meeting in Chicago has shown that it may be possible to predict risk of dementia using MRI with diffusion tensor imaging (DTI). About 50% of ... read more


Elective cesarean delivery increases the risk of overweight infant

Elective cesarean delivery is associated with the resulting child having an increased risk of or being overweight (high body mass index–for–age z score) at age 12 months, according to a prospective birth cohort study that looked at outcomes of elective and emergency cesarean ... read more


People with dystonia and spasticity may become immune to botulinum toxin treatment

A new study published online in the journal Neurology has shown that about 15% of people treated with botulinum toxin type A for cervical dystonia, blepharospasm, facial hemispasm or other types of dystonia and spasticity can develop an immune response to the treatment itself, which can make the treatment less effective or stop working entirely. Overall, 14% of the people ... read more


FDA cautions about differentiation syndrome associated with enasidenib used in AML patients

The life-threatening adverse effect known as differentiation syndrome is not being recognized by clinicians in patients receiving the acute myeloid leukemia (AML) drug enasidenib, says the US FDA. The symptoms of the syndrome include fever; cough; shortness of breath; swelling of the ... read more

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