Editor-in-Chief eMediNexus – Dr KK Aggarwal
2nd November 2019

The first triple combination therapy for cystic fibrosis

Dr KK Aggarwal, Recipient of Padma Shri

The first triple drug combination therapy - elexacaftor/ivacaftor/tezacaftor (Trikafta) – has been approved by the US FDA, for the treatment of patients 12 years and older with cystic fibrosis, who have at least one F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which comprises 90% of all patients who have cystic fiborsis.

Mechanism of action: The three drugs in the combination drug target the defective CFTR protein and enable the protein made by the CFTR gene mutation function more effectively...read more

Why daan or charity is important?

Dr KK Aggarwal, Recipient of Padma Shri

Srimad Bhagwad Gita has described four Yugas – Sat Yuga, Treta Yuga, Dwapar Yuga and Kal Yuga - depending upon the nature of the collective consciousness of the people. It describes four pillars of Dharma and they are truthfulness (satya), hard work (tapas), purity of mind (pavitrata) and charity (daya and daan)....read more

Video Of The Day : Indoor Pollution
Practice Updates

New WHO report to bolster efforts to tackle leading causes of urban deaths

A new report by the World Health Organization offers guidance and tools for urban leaders to tackle some of the leading causes of death in cities. The report, titled 'The Power of Cities: Tackling Non-Communicable Diseases and Road Traffic Injuries' is geared towards mayors,... read more

Sex ratio improves in country; birth and death rates dip

India has registered an improved sex ratio and a decline in birth and death rates with non-communicable diseases dominating over communicable in the total disease burden of the country, according to the Central Bureau of Health Intelligence's (CBHI) National Health Profile (NHP) 2019.... read more

Bedtime Dosing of Hypertension Meds Reduces CV Events

Taking antihypertensive medication at bedtime led to an almost halving of cardiovascular events in a new study. The Hygia Chronotherapy Trial is the largest ever study to investigate the effect of the time of day when people take their antihypertensive medication on the risk of cardiovascular events.... read more

Measles Erases 'Immune Memory' of Other Illnesses

Measles infection in unvaccinated children was associated with up to a 70% decline in antibodies to other pathogens following infection, researchers noted. After cases of severe measles, unvaccinated children lost a median... read more

High Court: Medical council can take action

The Medical Council of India and the West Bengal Medical Council can take action against three private hospitals for running a three-year postgraduate course in emergency medicine, apparently without their approval, Calcutta High Court said on Wednesday. In the same order,... read more

Drug-resistant E. coli bacteremia transmitted by fecal microbiota transplant

A new report published October 30, 2019 in the New England Journal of Medicine describes two patients in whom extended-spectrum beta-lactamase (ESBL)–producing Escherichia coli bacteremia occurred after they had undergone FMT in two independent clinical trials;... read more

Medical Voice

Call to Action to eliminate Lymphatic Filariasis by 2021

"Planning, commitment, vision, societal involvement and past experiences can help us achieve our goal of eliminating Lymphatic Filariasis from the country by 2021" said Dr. Harsh Vardhan, Union Minister for Health & Family Welfare as he inaugurated the day long National Symposium on the theme 'United to Eliminate Lymphatic Filariasis'...read more

eMedi Humor
Medicolegal Corner
eMedi Quiz
A. Mercury
B. Lead
C. Arsenic
D. Zinc
Lifestyle Updates
Inspirational Story 1: The seeker of truth
Inspirational Story 2: Is your hut burning?
"To watch 1500+ such videos, please visit www.medtalks.in"