eMedinewS27th April 2014, Sunday

Dr K K AggarwalPadma Shri, Dr B C Roy National Awardee and DST National Science Communication Awardee

Dr KK Aggarwal

President, Heart Care Foundation of India; Senior Consultant Physician, Cardiologist & Dean Medical Education Moolchand Medcity; Editor in Chief IJCP Group, Senior National Vice President, Indian Medical Association; Member Ethics Committee Medical Council of India, Chairman Ethical Committee Delhi Medical Council, Hony. Visiting Professor (Clinical Research) DIPSAR; Limca Book of Record Holder in CPR, Chairman (Delhi Chapter) International Medical Sciences Academy (March 10–13); Hony Director IMA AKN Sinha Institute (08–09); Hony Finance Secretary National IMA (07–08); Chairman IMA Academy of Medical Specialties (06–07); President Delhi Medical Association (05–06), President IMA New Delhi Branch (94–95, 02–04);
For updates follow at :  www.twitter.com/DrKKAggarwal, www.facebook.com/Dr KKAggarwal

NIH World Malaria Day Statement

The mosquito–borne disease continues to sicken and kill far too many people each year, most of them children. In 2012, roughly 207 million cases of malaria occurred worldwide resulting in 627,000 deaths, according to the World Health Organization (WHO).

In 2013, 97 countries had ongoing malaria transmission, placing 3.4 billion people at risk for the disease. And in a globally connected world, even people living in the United States can be at risk. In 2011, nearly 2,000 people in this country were diagnosed with malaria — the highest number since 1971. Virtually all of those cases occurred in U.S. residents or citizens who had travelled abroad.

The WHO World Malaria Day theme is "Invest in the Future. Defeat Malaria.

NIAID is supporting 21 anti-malaria treatment candidates in various stages of preclinical and clinical testing. Last year, NIH–supported researchers from 16 international institutions identified a new class of antimalarial compounds that target multiple stages of the malaria parasite’s lifecycle. Additionally, NIAID–supported investigators also identified the protein essential to all stages of the malaria parasite’s lifecycle. When tested in infected mice and nonhuman primates, a newly identified class of anti-malaria drug compounds inhibited the protein and stopped the development of the parasites. Further evaluation of these compounds is continuing. In addition, several investigational malaria treatments are undergoing clinical testing. For example, the novel anti–malaria drug DSM265 is being evaluated in a Phase I clinical trial through collaboration between NIH scientists and the nonprofit Medicines for Malaria Venture.

NIAID researchers are also targeting the malaria–spreading mosquitoes. For example, NIAID–funded researchers infected Anopheles stephensi mosquitoes with Wolbachia bacteria, which prevented malaria–causing parasites from developing in the mosquitoes. Moreover, the researchers demonstrated that the bacterial infection can be transferred between generations of mosquitoes, raising hope that the strategy could be employed in future malaria control strategies. NIAID–supported scientists have also demonstrated how mosquitoes are attracted to humans and identified compounds that, if developed further, could potentially mask human scent and lure the insects into traps.

Given that parasite resistance to the first–line malaria drug arteminisin has emerged in at least four countries, NIAID is simultaneously working to find new malaria drugs and develop methods for detecting resistance in an effort to slow its spread. In 2013, NIAID scientists working with French and Cambodian investigators developed two tests that can determine in three days whether the malaria parasites in a particular patient are resistant or susceptible to arteminisin. The tests offer significant advantages over current tests in terms of cost and time to diagnosis, and may be used for future studies designed to better understand the molecular basis of resistance and to screen new malaria drugs. NIAID investigators are also working with local investigators in Southeast Asia and Africa to study resistance in an effort to tailor treatment to a given region. An international team of researchers, including NIAID scientists, identified a genetic mutation that made some malaria–causing Plasmodium falciparum parasites in Cambodia resistant to arteminisin. Further study is under way to understand how the mutation causes resistance, whether it is present in other regions of the world, and how it might be addressed.

Insecticide resistance among mosquitoes — now present in more than 60 countries — is also a growing concern for malaria control efforts.

To assist on this front, NIAID–funded investigators have identified several compounds that repel mosquitoes and which could eventually be developed into alternatives to the commonly used repellent DEET.

A vaccine to prevent malaria is a primary goal of the NIAID malaria research agenda. One investigational vaccine, PfSPZ, which uses weakened malaria parasites delivered intravenously, was found to be safe and protective when tested in a small initial clinical trial in 57 adults last year.

NIAID investigators and other researchers recently described the protective immune response that occurs among children in Mali who are repeatedly exposed to malaria–infected mosquitoes based on where they live. The findings may help researchers develop future interventions to prevent or mitigate the effects of malaria infection. (Source: B.F. (Lee) Hall, M.D., Ph.D., and Anthony S. Fauci, M.D. National Institute of Allergy and Infectious Diseases)

News Around The Globe

National Interventional Council (NIC)

April 25th to 27th, Hotel Le Meridien, Kochi.

  • A study published online in Obesity Surgery has stated that almost all patients will have smaller appetite following gastric–bypass surgery; however, it also revealed that they will also experience that some foods do not taste or smell the same as they used to. Additionally, patients who developed food aversions, often to meat, lost more weight than their peers.
  • According to a new study, a commercial diet plan incorporating prepackaged foods, menu plans and counseling appeared to be better at helping people with type 2 diabetes lose weight than a typical diet. The commercial diet plan also led to better blood sugar control after a year.
  • Mild cognitive impairment (MCI), amnestic (aMCI) as well as nonamnestic (naMCI), may be associated with increased mortality, reports a new study. The association was stronger in patients with cognitive decline not affecting memory. The findings will be presented at the American Academy of Neurology (AAN) 66th Annual Meeting in Philadelphia, Pennsylvania, April 26 to May 3.
  • A novel study published online April 22 in JAMA has revealed that acetazolamide has the potential to improve vision in patients with idiopathic intracranial hypertension (IIH) and mild vision loss.
  • A novel study from Japan has stated that tacrolimus 0.1% eye drops could lead to significant improvement in refractory allergic conjunctivitis with proliferative lesions and corneal involvement. The mean total score of clinical signs decreased from 15.3 (out of 30) at treatment initiation to 5.9 at the last observation, and the mean total clinical symptom score decreased from 8.1 (out of 18) at baseline to 1.8 at the last observation with one drop of tacrolimus twice daily.

Rabies News (Dr A K Gupta)

Is there a need to alter the dose or schedule of any concomitant medication during IDRV?

There is no need to alter the dose or schedule of any concomitant medication during IDRV.

Cardiology eMedinewS

  • The American Heart Association (AHA) has released a scientific statement addressing the diagnosis and treatment of fetal cardiac disease. The statement highlights that diagnosis of cardiac disease in the fetus is mostly made with ultrasound; however, newer techniques are now available. Also, strategies for delivery room care now enable stabilization of high–risk fetuses and contribute to improved outcomes.
  • Giving adrenaline to patients after they suffer a cardiac arrest outside the hospital–setting does not increase their odds of surviving long–term, reports a new research published in the journal Resuscitation.

Pediatrics eMedinewS

  • A study published in Arthritis Care & Research has revealed that prenatal exposure to tobacco smoke, air pollution, and occupational contaminants is linked with an increased risk of children later developing juvenile dermatomyositis. Of note, offspring of mothers who smoked during pregnancy had a 13 times increased risk of being diagnosed with chronic inflammatory disease of the muscles and skin.
  • Children with conductive hearing loss fitted with an FDA–approved magnet–based bone–anchored hearing device have been noted to experience significant skin issues, reported doctors from the Medical College of Wisconsin. However, the doctors have found ways to avoid these problems. These include initial fitting with the lowest magnet strength possible, graduated wearing schedule, counseling, and wearing soft–band device, among others.

Dr K K Spiritual Blog

The spiritual prescription "I am sorry"

Two hardest words for a doctor to say: "I’m sorry."

Most defense lawyers counsels doctors not to apologize to patients. Their view is that if you say you’re sorry for something, you are implicitly taking some degree of responsibility for whatever has happened or in other words you are pleading guilty. The complainant’s lawyers may use a doctor’s apology to the maximum extent possible to show the doctor knew what they did was wrong. The usual approach is deny and defend.

But

  1. Apologizing after a medical error is the humane thing to do.
  2. Patients often sue simply because it’s the only way to find out what went wrong.
  3. Erecting a wall of silence is "enough to make someone very angry. And it’s awfully easy for an angry person to find a lawyer who will listen to them. At that point, it’s too late for sorry.
  4. Over 35 states in the USA have passed laws prohibiting doctors’ apologies from being used against them in court. {apology laws)
  5. By promptly disclosing medical errors and offering earnest apologies and fair compensation one can hope to restore integrity to dealings with patients, make it easier to learn from mistakes and dilute anger that often fuels lawsuits.

Apology the spiritual answer

  1. The word ‘sorry’ is synonymous with apology.
  2. To err is human, to admit one’s error is superhuman.
  3. Sorry should be heart felt and not ego felt. You should not only say sorry but it should look like that you are sorry.
  4. Tremendous courage is entailed to face the victim of our wrong doing and apologise.
  5. It is generally seen that those who are in harmony with their life and consequently with themselves, find it easier to say ‘I’m sorry’. They are the positive, conscientious ones who are at peace only after making amends for their misdeeds.
  6. The word ‘sorry’ in itself is imbued with so much potential and power. Within a fraction of a second, grave mistakes are diluted, tepid and estranged relations are brought alive, animosity and rancour are dissolved, misunderstandings resolved and tense situations ease out resulting in harmony and rapprochement.
  7. To forgive and forget is a common spiritual saying
  8. Remember we all do mistakes and seek forgiveness form GOD every day.

Wellness Blog

Drinking coffee prevents Parkinson’s disease

Nicotine present in the tobacco has been used for its medicinal value for quite some time for diseases like Parkinson’s disease and ulcerative colitis. A study from University of Miami School of Medicine, USA, now has shown that people from families prone to Parkinson’s disease are less likely to develop the disease if they drink coffee on a regular basis.

Both coffee and nicotine have a link with dopamine in the brain. Dopamine is a chemical that decreases in patients with Parkinson’s disease.

It is possible that people who are going to have Parkinson’s disease have lower levels of dopamine. Those with low levels of dopamine may be more likely to enjoy caffeine.

Parkinson’s disease is caused when brain cells that produce dopamine die. The disease is progressive, affecting about one percent of people older than 65.

Symptoms start out with shaking and can progress to paralysis. There is no cure, although a number of drugs can make symptoms better for a time.

Inspirational Story

Laughter is the Best Medicine

Many years ago, Norman Cousins was diagnosed as "terminally ill". He was given six months to live. His chance for recovery was 1 in 500.

He could see the worry, depression and anger in his life contributed to, and perhaps helped cause, his disease. He wondered, "If illness can be caused by negativity, can wellness be created by positivity?"

He decided to make an experiment of himself. Laughter was one of the most positive activities he knew. He rented all the funny movies he could find – Keaton, Chaplin, Fields, the Marx Brothers. (This was before VCRs, so he had to rent the actual films.) He read funny stories. He asked his friends to call him whenever they said, heard or did something funny.

His pain was so great he could not sleep. Laughing for 10 solid minutes, he found, relieved the pain for several hours so he could sleep. He fully recovered from his illness and lived another 20 happy, healthy and productive years. (His journey is detailed in his book, Anatomy of an Illness.) He credits visualization, the love of his family and friends, and laughter for his recovery.

Some people think laughter is a waste of time. It is a luxury, they say, a frivolity, something to indulge in only every so often. Nothing could be further from the truth. Laughter is essential to our equilibrium, to our well–being, to our aliveness. If we’re not well, laughter helps us get well; if we are well, laughter helps us stay that way.

Since Cousins’ ground–breaking subjective work, scientific studies have shown that laughter has a curative effect on the body, the mind and the emotions. So, if you like laughter, consider it sound medical advice to indulge in it as often as you can. If you don’t like laughter, then take your medicine – laugh anyway.

Use whatever makes you laugh – movies, sitcoms, Monty Python, records, books, New Yorker cartoons, jokes, friends. Give yourself permission to laugh – long and loud and out loud – whenever anything strikes you as funny. The people around you may think you’re strange, but sooner or later they’ll join in even if they don’t know what you’re laughing about.

Some diseases may be contagious, but none is as contagious as the cure… laughter.

ePress Release

Elderly Beware

Anti–cholinergics, a commonly prescribed group of drugs, may cause elderly people to "slow down" in their daily physical activities, said Padma Shri, Dr. B C Roy National Awardee & DST National Science Communication Awardee, Dr. K K Aggarwal, President Heart Care Foundation of India and Sr National Vice President Indian Medical Association.

Two reports from Wake Forest University School of Medicine support findings that anti–cholinergic drugs – Used to treat acid reflux, Parkinson’s disease and urinary incontinence –– may cause older people to lose their thinking skills more quickly than those who do not take the medicines.

Anti–cholinergic drugs work by stopping acetylcholine, a chemical that enhances communication between nerve cells in the brain, from binding to its receptors in nerve cells.

Older adults taking anti–cholinergics become more likely to walk more slowly and to need help in other daily activities. These results are true even in older adults who have normal memory and thinking abilities.

For older adults taking a moderately anticholinergic medication, or two or more mildly anticholinergic medications, their function is similar to that of someone three to four years older.

Common anticholinergic medicines include blood pressure medication, nifedipine; the stomach antacid, ranitidine, and the incontinence medication, tolterodine.

Cholinesterase inhibitors, a family of drugs used to treat dementia by increasing levels of acetylcholine include donepezil, galantamine, rivastigmine and tacrine. About 10 percent of patients may be taking tolterodine and dozepezil together. The two drugs are pharmacological opposites, which led to the hypothesis that the simultaneous treatment of dementia and incontinence could lead to reduced effectiveness of one or both drug

About HCFI : The only National Not for profit NGO, on whose mega community health education events, Govt. of India has released two National commemorative stamps and one cancellation stamp, and who has conducted one to one training on" Hands only CPR" of 88972 people since 1stNovember 2012.

The CPR 10 Mantra is – "within 10 minutes of death, earlier the better; at least for the next 10 minutes, longer the better; compress the centre of the chest of the dead person continuously and effectively with a speed of 10x10 i.e. 100 per minute."

Zee News – Health Wealth Shows

Alcohol
Cancer Prevention
Depression
Paralysis
Pneumonia
Potbelly Obesity
Sudden Cardiac Death
Safe Drugs
Safe Holi
Vitamin D
Vitiligo
Fluid Intake

 

Total CPR since 1st November 2012 – 88972 trained

cpr10 Mantra The CPR 10 Mantra is – "within 10 minutes of death, earlier the better; at least for the next 10 minutes, longer the better; compress the centre of the chest of the dead person continuously and effectively with a speed of 10×10 i.e. 100 per minute."

CPR 10 Success Stories

Ms Geetanjali, SD Public School
Success story Ms Sudha Malik
BVN School girl Harshita
Elderly man saved by Anuja

CPR 10 Videos

cpr 10 mantra
VIP’s on CPR 10 Mantra Video

Hands–only CPR 10 English
Hands–only CPR 10 (Hindi)

emedipicstoday emedipics

World Earth Day Celebration at DAV Public School, RK Puram, New Delhi.

press release

FDA panel recommends first drug for HIV prevention

video of day video of day

 

IJCP Book of Medical Records

IJCP Book of Medical Records Is the First and the Only Credible Site with Indian Medical Records.

If you feel any time that you have created something which should be certified so that you can put it in your profile, you can submit your claim to us on :

 

Make Sure

Situation: A patient with dengue fever developed shock.
Reaction: Oh my God! Why was the blood pressure 90/80 ignored?
Lesson: Make sure that a pulse pressure of less than 20 is not ignored, it is an impending sign that the patient is going into shock.

eMedinewS Humor

Never be rude to anyone

An American tourist asked a boat guy in Zanzibar, "Do you know Biology, Psychology, Geography, Geology or Criminology?"

The boat guy said, "No. I don’t know any of these."

The tourist then said, "What the hell do you know on the face of this Earth? You will die of illiteracy!"

The boat guy said nothing. After a while the boat developed a fault and started sinking. The boatman then asked the tourist, "Do you know Swimology and Escapology from Crocodiology?"

The tourist said, "No!"

The boat guy replied, "Well, today you will Drownology and Crocodiology will eat you. I will not Helpology and you will Dieology because of your Badmouthology."

Quote of the Day

The best thing about dreams is that fleeting moment, when you are between asleep and awake, when you don’t know the difference between reality and fantasy, when for just that one moment you feel with your entire soul that the dream is reality, and it really happened. Johann Wolfgang von Goethe

 

Twitter of the Day

Dr KK Aggarwal: Diabetes is a progressive disease http://youtu.be/NMIK16PyBrY?a via @YouTube
Dr Deepak Chopra: You were created to be completely loved and completely lovable, for your whole life http://bit.ly/DC_Ananda #ananda

 

eMedi Quiz

A measure of location which divides the distribution in the ratio of 3:1 is:

1. Median.
2. First quartile.
3. Third quartile.
4. Mode.

Yesterday’s Mind Teaser: Which of the following is not a post transcriptional modification of RNA?

1. Splicing.
2. 5’ Capping.
3. 3’ polyadenylation.
4. Glycosylation.

Answer for yesterday’s Mind Teaser: 4. Glycosylation.

Correct answers received from: Dr A K (Jain)Diwaker, Dr Jainendra Upadhyay, Dr Poonam Chablani, Dr KV Sarma.

Answer for 25th April Mind Teaser: 3. Leaves extension at elbow joint intact.

Correct answers received from: Dr Kabir.

Send your answer to ijcp12@gmail.com

medicolegal update

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medicolegal update

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medicolegal update
  1. Dear Sir, Very good Coverage of NIC 2014. Regards: Dr K Sharma
cardiology news

Media advocacy through Web Media

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