Editor-in-Chief eMediNexus – Dr KK Aggarwal
27th March 2019
Screening test for endothelial function

Dr KK Aggarwal, Padma Shri Awardee

Brachial artery ultrasound is a commonly used and widely accepted method to evaluate the peripheral macrovascular endothelial function.

Inflating the blood pressure cuff at suprasystolic pressures for 5 minutes occludes the upper arm proximal to the ultrasound measurement. When this occlusion is released, endothelial-dependent, nitric oxide NO-driven, flow-mediated dilation (FMD) of the brachial artery occurs due to an increase in shear stress. Both diameter and blood velocity are measured before and after occlusion at the end of the diastole. The results are reported as a percent change from baseline.....read more

Postmenopausal women at high risk of fractures should be treated for osteoporosis

Dr KK Aggarwal, Padma Shri Awardee

Osteoporosis is often a silent disease and is responsible for minimal trauma fractures in the hip, spine and ribs later in life.

In contrast to senile osteoporosis, osteoporosis occurs much more in the spine in postmenopausal osteoporosis, which is a cancellous bone. In senile osteoporosis, bones are 50-50, cancellous as well as cortical. Osteoporosis occurs both in the spine and hip. The commonest fractures in osteoporosis are spine fractures in postmenopausal women followed by fractures in hip and wrist....read more

Practice Updates

Govt notifies new rules for drugs and clinical trials

New Delhi, Mar 25 : Aimed at promoting clinical research in the country, the Health Ministry on Monday notified New Drugs and Clinical Trials Rules, 2019 reducing the time for approving applications to 30 days for drugs manufactured in India and 90 days for those developed outside the country..... read more

Ebola outbreak in eastern Democratic Republic of Congo tops 1,000 cases

As of March 24, 2019, public health officials have documented that the Ebola outbreak in eastern Democratic Republic of Congo (DRC) has surpassed 1,000 cases; the current total number of confirmed and probable cases is 1009, including 625 deaths and 318 survivors.... read more

Cabo Verde launches first "solidarity chain" in Africa with a flash mob promoting universal health coverage

Led by the Cabo Verde's Minister of Sports and the World Health Organization (WHO) Regional Director for Africa, hundreds of people held hands and stood side by side in an umbrella shape on Quebra Canela beach in Praia to show their solidarity for universal health coverage..... read more

Walking downhill after meals boosts bone health in postmenopausal women with diabetes

Walking downhill after eating can reduce bone resorption, the process in which old bone is broken down and removed from the body, in postmenopausal women with diabetes, according to research presented at ENDO 2019, the annual meeting of the Endocrine Society,...read more

AAP/AHA policy statement to reduce consumption of sugary drinks in children

In a joint policy statement published online March 25, 2019 in Pediatrics, the American Academy of Pediatrics (AAP) and the American Heart Association (AHA) endorsed a suite of public health measures including excise taxes, limits on marketing to children,... read more

Children develop PTSD when they 'overthink' their trauma

Children are more likely to suffer post traumatic stress disorder (PTSD) if they think their reaction to traumatic events is not 'normal', according to a new research published in the Journal of Child Psychology and Psychiatry on March 26, 2019.... read more

Replacing sitting time with physical activity associated with lower risk of death

A new study from the American Cancer Society suggests that replacing modest amounts of sitting time with even light physical activity may have the potential to reduce the risk of premature death among less active adults..... read more

Medical Voice

1. More early research into a possible male contraceptive pill has been presented here at ENDO 2019: The Endocrine Society Annual Meeting. The results suggest that this pill, a modified testosterone which combines two hormonal activities in one,.... read more

eMedi Humor
Medicolegal Corner
eMedi Quiz
1.Reduced energy production.
2. Decreased production of 2,3-bisphosphoglycerate.
3. Reduced synthesis of hemoglobin.
4. Low levels of oxygen.
Lifestyle Updates
Inspirational Story 1: : A box of kisses
Inspirational Story 2: Emotional management
Sleep better and adequately to reduce the risk of Alzheimer’s disease
A healthy lifestyle adopted early in life builds up cognitive reserve for later life
New Delhi, 26th March 2019: Adequate sleep clears the accumulation of amyloid beta proteins that are known to cause Alzheimer's disease (AD), finds a new study. The results of this study are published in the Journal of Neurophysiology. A better understanding of this connection may lead to potential diagnostics and therapeutics for AD and other neurodegenerative diseases and dementia. Sleep helps the body eliminate excess amyloid beta before too much accumulates in the brain.

Older people who get less deep sleep have higher levels of the brain protein tau, a sign of cognitive decline and AD, according to another study.

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