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23rd march 2010, Tuesday
Do financial interests result in positive results in scientific research?
I recently came across an interesting peace of information in Science Daily as to how researches are done in the United States. I thought of sharing the same with you all.
Over 94% of the researchers who provided positive results for the anti–diabetic drug rosiglitazone had financial relationships with pharmaceutical companies, as per a research published online in the British Medical Journal. However, the article acknowledges that financial relationships may not necessarily be the reason for positive research results.
In 2007, a large scale review of rosiglitazone showed that use of the drug led to a significant increased risk of heart attacks. This led to further studies and policies were also developed to encourage disclosure of such financial conflicts of interest.
Researchers at the Mayo Clinic assessed over 200 articles on rosiglitazone to explore a possible link between authors’ financial conflicts of interest and their views on the safety of the drug. They found that 45% of the study authors had financial conflicts of interest and 23% of these did not disclose this information.
Almost all (94%) authors who had favourable views on the safety of rosiglitazone were more likely to have a financial conflict of interest with a pharmaceutical company than were authors who had unfavourable views.
The study concluded that disclosure rates for financial conflicts of interest were unexpectedly low, and there was a clear and strong link between the orientation of authors’ expressed views on the rosiglitazone controversy and their financial conflicts of interest with pharmaceutical companies. The researchers further stated that these findings, while not necessarily causal, underscore the need for further progress in reporting in order for the scientific record to be trusted.
Dr KK Aggarwal
Laughter the best medicine
Actual medical record
The patient has no past history of suicides.
Formulae in Critical Care
Stroke index (SI)
Milestones in Orthopedics
George S. Phalen (1911–1998) was an American hand surgeon remembered for his work on carpal tunnel syndrome (CTS) including his description of Phalen’s maneuver. Although it had been described previously by James Paget in 1854 and James Jackson Putman in 1880, Phalen improved the understanding of the etiology of CTS. The condition became widely known among the general public in the 1990s because of the rapid expansion of office jobs.
Mistakes in Clinical Practice
Lack of leading zero (.X mg) Decimal point may be missed. Instead write as 0.X mg
Lab Test (Dr Naveen Dang)
5–HIAA is used to help diagnose and monitor treatment for a serotin secreting carcinoid tumor.
List of Approved drug from 1.01.2009 to 31.10.2009
ZEN IMMUNE–FACT SHEET
Zen Immune Beauty helps improve the brittleness of nails and increase the hair tensile strength, thus preventing hair loss. It stimulates regeneration of hair roots, helps prevention of comedone formation and post comedone skin scarring in acne vulgaris.
Advertising in eMedinewS
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Will be organized at Maulana Azad Medical College, New Delhi on July 4, 2010, Sunday to commemorate Doctors’ Day. The speakers, chairpersons and panelists will be doctors from NCR, who have been past and present Padma awardees.
The second eMedinewS–revisiting 2010 conference will be held at Maulana Azad Medical College, New Delhi on January 2, 2011. The event will have a day–long CME, Doctor of the Year awards, cultural hungama and live webcast. Suggestions are invited.
NATIONAL SEMINAR ON STRESS PREVENTION (17–18 April). Over 400 registrations already done.
A Stress Prevention Residential Seminar cum spiritual retreat with Dr KK Aggarwal and Experts from Brahma Kumaris will be organized from April 17–18, 2010.
Co–organizers: eMedinews, Brahma Kumaris, Heart Care Foundation of India, IMA New Delhi Branch and IMA Janak Puri Branch, IMSA (Delhi Chapter)
Venue: Om Shanti Retreat Centre, National Highway 8, Bilaspur Chowk, Pataudi Road, Near Manesar.
Timings: On Saturday 17th April (2 pm onwards) and Sunday 18th April (7 am–4 pm). There will be no registration charges, limited rooms, kindly book in advance; stay and food (satvik) will be provided. Voluntary contributions welcome. For booking e–mail and SMS to Dr KK Aggarwal: 9811090206, email@example.com BK Sapna: 9811796962, firstname.lastname@example.org
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