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21st  September 2016
Can Chikungunya be fatal? What published literature has to say 
 
  • “Torres et al describe four Venezuelan patients with a severe and/or lethal course who exhibit unusual manifestations of the disease. Case 1 describes a 75 year-old man with rapid onset of septic shock and multi-organ failure. Cases 2 and 3 describe two patients with rapid aggressive clinical course who developed shock, severe purpuric lesions and a distinct area large of necrosis in the nasal region. Case 4 depicts a splenectomized woman with shock, generalized purpuric lesions, bullous dermatosis and acronecrosis of an upper limb. Chikungunya fever in the Western hemisphere may also associate with atypical and severe manifestations. Some patients experience a life-threatening, aggressive clinical course, with rapid deterioration and death due to multisystem failure.” Torres JR, Leopoldo Códova G, Castro JS, et al. Chikungunya fever: Atypical and lethal cases in the Western hemisphere: A Venezuelan experience. IDCases. 2014 Dec 18;2(1):6-10. 
  •  “Chikungunya virus is a mosquito-borne alphavirus which causes fever, rash, and arthralgia. In the past, life-threatening complications were very rarely reported. However, during the recent worldwide outbreaks, there have been several reports of unusually severe complications and deaths. Malaysia is experiencing a nationwide outbreak of CHIKV, with over 10 000 patients affected since April 2008. Sam et al report the first case of culture-confirmed CHIKV-associated death in Malaysia, in a patient with fever, rash, acute exacerbation of pre-existing heart failure, rhabdomyolysis, and multiple organ failure. CHIKV infections may cause atypical, severe or fatal presentations.” Sam IC, Kamarulzaman A, Ong GS, et al. Chikungunya virus-associated death in Malaysia. Trop Biomed. 2010 Aug;27(2):343-7.
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Reversal of heart disease 
 
New Delhi, September 20, 2016: Heart disease is reversible if lifestyle modifications are made in a timely manner. Nine potentially modifiable risk factors of heart attacks have been identified, which include smoking, dyslipidemia, hypertension, diabetes, abdominal obesity, psychosocial factors, regular alcohol consumption, lack of adequate fruits and vegetables in the diet and a sedentary lifestyle. Over 90% of Indians suffer their first heart attack due to one or several of these lifestyle irregularities. Modifying one’s bad habits can go a long way in helping prevent the onset of heart diseases.
 
Speaking on this topic, Padma Shri Awardee, Dr. KK Aggarwal, President HCFI & President Elect IMA said, "Majority of the known risk factors of heart disease are modifiable. The reasons for the rising incidence of premature heart disease amongst today's generation are their unhealthy life choices.
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