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Dr k k Aggarwal Special

CMAAO Coronavirus Facts and Myth Buster: Vaccines can trigger reactogenic thrombo-inflammation

Dr KK Aggarwal President CMAAO, HCFI
19th March 2021
With input from Dr Monica Vasudev
1470: The Pharmacovigilance Risk Assessment Committee (PRAC) of the European Medicines Agency (EMA) is looking into the cases of thromboembolic events tied to AstraZeneca's COVID-19 vaccine. However, it still maintains that the benefits outweigh risks.
As of March 10, 30 cases of thromboembolic events were reported among about 5 million individuals administered the AstraZeneca vaccine in the European Economic Area, including European Union (EU) countries and Iceland, Liechtenstein, and Norway...Read more »
Dr k k Aggarwal

World COVID Meter 18th March 2021: Acute manageable immunogenic thrombogenic inflammatory contagious novel viral disease pandemic

Dr KK Aggarwal, President CMAAO, HCFI and Past National President IMA
19th March 2021
CMAAO: In susceptible high-risk (pro-inflammatory and/or pro-coagulative) individuals, reactogenic vaccines can trigger transient thrombo-inflammation lasting first few (up to four) days. COVID Vaccine: non-replicative, non-repetitive dose, spike gene mRNA/spike gene DNA to mRNA/whole killed virus, reactogenic vaccine Cases: 1M April 2, 2M April 15, 3M April 27, 4M May 8, 5M May 20, 6M May 30, 7M June 7, 8M June 15, 9M June 22, 10M June 29th, 11M July 4, 12M July 8, 13M July 13, 14M July 17, 15M July 23, 16M July 25, 17M July 29, 18M August 1, 19M August 6, 20M August 10, 21M August 16, 22M August 19, 23M August 21, 24M August 27, 25M August 30, 26M September 3, 27M September 7,...Read more »
Dr k k Aggarwal

Factors associated with increased susceptibility of Drug Induced Liver Injury

19th March 2021 Gastroenterology Hepatology Multispeciality
Although drug-induced liver injury (DILI) has a rare occurrence, it is potentially a life threatening adverse drug reaction. The morphologic characteristic of DILI are similar to acute or chronic liver disease while its histopathologic features may be identical to those of other causes of liver injury,... Read more »
Cough Update

Clinical efficacy of the accompanying flavor in a cold and cough syrup

19th March 2021 Allergy & Immunology Multispeciality
Medications available over-the-counter (OTC) for the treatment of colds and coughs are not only effective in giving the symptomatic relief but are also pleasant to take as to encourage compliance. A new syrup formulation for the symptomatic relief of colds, chills, and productive cough was developed containing paracetamol,... Read more »

News From All Specialities

New clinical and service delivery recommendations for HIV prevention, treatment and care released by WHO

19th March 2021 Business and Medicine Public Health
The World Health Organization (WHO) has published new guidelines that provide new and updated recommendations on the use of point-of-care testing in children below 18 months of age and point-of-care tests to follow the treatment in people living with HIV; the treatment monitoring algorithm;... Read more »

Experts approve Janssen COVID-19 vaccine

19th March 2021 Emergency Medicine Pathology & Lab Medicine
The Janssen COVID-19 shot has been publicly approved for international use by UN health agency expert advisory board, SAGE. Experts also alleviated concerns over clotting events that are being linked with COVID-19 vaccines by some countries, without conclusive evidence... Read more »

COVID-19 reinfection rare, but more common in older individuals: Study

19th March 2021 Pathology & Lab Medicine Emergency Medicine
Most of the people who have had COVID-19 are protected against getting the infection again for at least six months, reported a study published in the Lancet; however, older individuals appear to be more vulnerable to reinfection compared to younger people. The study noted that only 0.65% of the patients tested positive a second time after previously... Read more »

India records its highest surge in COVID cases in 102 days

19th March 2021 Pathology & Lab Medicine Pulmonary Medicine
India recorded its highest COVID-19 case numbers in 102 days on Wednesday as 35,886 patients tested positive for the virus. Maharashtra continues to be the worst-hit state, accounting for 64% of the daily new cases in the country. Maharashtra reported 23,179 new cases,... Read more »

Baby Born to Partially Vaccinated Mother Has COVID Antibodies

19th March 2021 Pathology & Lab Medicine Pharmacists
A baby girl born 3 weeks after her mother was vaccinated with the first dose of the Moderna COVID-19 vaccine has antibodies against the virus, reports a pre-print paper published on the medRxiv server. The paper hasn't been peer-reviewed yet. The mother is a healthcare worker in Florida who developed COVID-19 antibodies after receiving the vaccine dose... Read more »

Medicolegal Corner


How is consent documented?

19th March 2021
Patients may not be able to precisely remember all the facts disclosed during a discussion. Therefore, a physician must document the content of informed consent sessions. The informed consent discussion and its documentation should be done by the physician who is going to perform the procedure... Read more »

eMedi Humor


Funny Definitions

19th March 2021
Intoxication: Euphoria at getting a tax refund, which lasts until you realize it was your money to start with.
Hipatitis: Terminal coolness.
Dopeler effect: The tendency of stupid ideas to seem smarter when they come at you rapidly... Read more »

eMedi Quiz


An increase in which of the following parameters will shift the O2 dissociation curve to the left:

19th March 2021
1. Temperature.
2. Partial pressure of CO2
3. 2,3 DPG concentration. ... Read more »

Lifestyle Updates


eWellness: A slight move is all that matters

19th March 2021
Middle-aged women who tend to move around more in their daily life have lower levels of intra-abdominal fat, which is a known risk factor for heart disease. A slight modification in daily routine - reducing the time watching TV or increasing the walk time to work - can make a difference in the long-term health... Read more »

eSpiritual: The soul characteristics (Absolute Existence –Absolute Knowledge)

19th March 2021
Satt means ‘truth or knowingness’
Chitta means ‘consciousness-based’
Ananda means ‘bliss or inner happiness’... Read more »

Inspirational: The Three Fish

19th March 2021
There were three big fish living in a lake who were very close friends. They were quite different from one another. The first one believed in fate and thought that things cannot be changed; what had to happen will happen, no matter what, he thought. The second one was intelligent. He was confident that he knew how to solve a problem with his intelligence... Read more »


Medical voice

Doctors Survey

Question 1 : Which of these courses would you pay for - You can select multiple options
How to modernize clinic
Growing your digitize you clinic and practice...
Medical voice

How Corona Aware Are You

Question 1 : How confident are you that you could recognize and respond to a potential coronavirus case?
Very confident
Moderately confident...


From Other Newsletter

Recovery Digest


US dietary advisory committee recommends no added sugar until two years of age

A US government advisory group has issued its first-ever set of dietary guidelines for infants and toddlers. The plan from the 2020 Dietary Guidelines Advisory Committee recommends that children under two years of age should not be given any added sugar. It further states that infants should be fed only breast milk for the first six months, where possible... Read more »



Accelerated versus delayed renal replacement therapy: What should you go for?

While some recommend to initiate renal replacement therapy (RRT) as soon as severe acute kidney injury, on the other hand some advocate a delayed strategy wherein they suggest waiting until the patient develops an indication for dialysis.... Read more »



Impact of Moisturizing Skincare on Skin Barrier Function in Infants

Newborn skin is dry and undergoes significant changes in sebum. These changes are known to cause problems such as diaper dermatitis, seborrheic eczema and prickly heat in more than 50% of newborns. Routine bathing and moisturizer use are some of the preventive measures for such conditions in newborns... Read more »



Effect of Cissus quadrangularis on fracture union in a young male - Case report

Cissus quadrangularis is rich in anabolic steroids, calcium, and phosphorus. Stem extracts of the herb are often used for early repair of fractures. In a case report published in the International Journal of Research in Orthopaedics, authors assessed the effect of C. quandrangularis in advancing fracture union and reduction in pain and swelling... Read more »

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