Long-term benefits with early and intensive treatment of rheumatoid arthritis
Results of a 23-year follow-up of the COBRA (COmbinatietherapie Bij Rheumatoide Artritis) trial presented at the Annual European Congress of Rheumatology (EULAR 2018) show that early, intensive treatment of rheumatoid arthritis has long-term benefits including the normalization of mortality to levels consistent with the general population..... read more
Patients with severe atopic eczema increases risk of heart disease
Severe and predominantly active atopic eczema is associated with an increased risk of cardiovascular outcomes, says a study published in The BMJ, online May 23, 2018. In the study, patients with severe atopic eczema were at a 20% increased risk of stroke, 40-50% increased risk of unstable angina, myocardial infarction, atrial fibrillation and cardiovascular death and 70% increased risk of heart failure.
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First guidelines on the use of ketamine for acute pain management
Intravenous ketamine infusions can be used for acute pain management - as a stand-alone treatment, as an adjunct to opioids, and as an intranasal formulation, according to consensus guidelines published onlineJune 7, 2018in Regional Anesthesia and Pain Medicine..... read more
Crohn’s disease occurring after 55 years of age has ulcerative colitis-like characteristics
Late-onset Crohn’s disease, onset at age 55 years or older, is a subgroup distinct in genetic and behavioral risk factors with ulcerative colitis-like characteristics, says a study published online May 30, 2018 in Inflammatory Bowel Diseases.... read more
Presence of nonexudative neovascularization predisposes to development of exudative changes
In this prospective observational study of patients with unilateral age-related macular degeneration, the estimated annual incidence of fellow eye involvement was 18.1% and 2.0% in those with and without nonexudative neovascularization, respectively. The presence of nonexudative neovascularization predisposes to the development of exudative changes, but treatment should be started only when exudation develops. These findings were published online June 7, 2018 in JAMA Ophthalmology.
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