Editor-in-Chief eMediNexus – Dr KK Aggarwal
18th April 2019
Drug Safety Update

Dr KK Aggarwal, Padma Shri Awardee

SGLT2 inhibitors

Citing concerns raised by the US FDA and Health Canada regarding safety of SGLT2 inhibitors used for type 2 diabetes, the DCGI has issued a safety warning (F. No. 12-74/13-DC dated 25.3.19) and asked manufacturers of SGLT2 inhibitors to include the following warning in the package insert and promotional literature of these drugs:

"Warning: Cases of a rare but serious infection of the genitals and area around the genitals have been reported with this class of type 2 diabetes medicines i.e. sodium-glucose cotransporter-2 (SGLT-2) inhibitors. This serious rare infection, called necrotizing fasciitis of the perineum, is also referred to as Fournier’s gangrene.”....read more

Can benzodiazepines, opioids and muscle relaxants be combined in one patient?

Dr KK Aggarwal, Padma Shri Awardee

The answer is No. This can be deadly. Never prescribe all three drugs to one patient. If a patient overdoses on opioids, the doctor who prescribed them can expect a review of records. Prescribing two of the three drugs is even more risky.

If the combination is truly medically necessary, then your rationale for prescribing them should be documented.

Never prescribe even one of these medications without performing and documenting a thorough assessment and diagnosing a condition that necessitates their prescription. ...read more

Practice Updates

A mobile phone app that discovers disease and saves lives in Africa

What if a mobile phone could prevent a health epidemic? It may sound like science fiction, but the World Health Organization's (WHO) Polio Geographic Information System (GIS) Technology is doing just that in 43 countries in Africa..... read more

CALF now a national reference lab for milk

Vadodara/ Anand: The Food Safety and Standards Authority of India (FSSAI) has recognized CALF, a Anand-based laboratory of the National Dairy Development Board (NDDB) as a national reference laboratory (NRL) for dairy and dairy products. With FSSAI’s latest order, CALF has become the only NRL in the country for milk and milk products..... read more

Labeling added sugars content on packaged foods and beverages could lower risk of heart disease and diabetes

A label showing added sugars content on all packaged foods and sugary drinks could have substantial health and cost-saving benefits in the United States over the next 20 years, according to a new study published April 15, 2019 in the journal Circulation. The researchers predict that between 2018 and 2037,... read more

Sleeping pills linked to increase in use of antihypertensive medications in older adults

A prospective cohort study published online on March 25, 2019 in Geriatrics and Gerontology International has shown an association between the use of sleeping tablets by older hypertensive adults and subsequent increase....read more

Diabetes is a risk factor for fragility fractures in the frail

Participants with type 2 diabetes were significantly frailer than individuals without diabetes. Frailty increases the risk of fragility fracture and enhances the effect of diabetes on fragility fractures. Particular attention should be paid to diabetes as a risk factor for fragility fractures in those who are frail,....read more

Medical Voice

1. The High Court has asked the Jammu and Kashmir government to respond to a Public Interest Litigation seeking directions to allow sale and usage of e-cigarettes in the state. A division bench of Chief Justice Gita Mittal and Justice Tashi Rabstan granted six weeks to the government to file the response after state’s additional advocate General Shah Aamir sought the time. .... read more

IDEJ Update

Indian Diabetes Educator Journal (IDEJ), 1st of its kind in India aims to keep the members of diabetes care team abreast with concepts of DSME (Diabetes self-management education) and DSMS (Diabetes self-management support). IDEJ has set a new benchmark in educating the diabetes educators about evolving the concept of DSME- reaching to more than 25000 through Digital and Print Medium..... read more

eMedi Humor
Medicolegal Corner
eMedi Quiz
1. Slick’s maneuver is not required.
2. Pre-oxygenation is mandatory.
3. Suxamethonium is contraindicated.
4. Patient is mechanically ventilated before end tracheal incubation.
Lifestyle Updates
Inspirational Story 2: Weakness or Strength?
A 3 dimensional approach to Management of Diabetes
Violence against doctors is unacceptable but creating a positive communication channel with patients is key
Patients must understand that doctors are also humans and not Gods who can save lives under every adverse circumstance
New Delhi, 17 April 2019: In a recent directive issued by the Principal Secretary of Health and Family Welfare, Govt of NCT of Delhi, HODs of hospitals or medical institutions will file FIR against any incidents of abuse or violence by patients or their attendants. As per the directive, no individuals, be it hospital staff or doctors can file the FIR. It will be incumbent on the MS/Director of the institution to ensure that FIR is registered immediately in such cases and any non-compliance will be dealt with seriously.

A recent survey by the Indian Medical Association (IMA) revealed that nearly 75% of doctors in India have faced some form of violence or threat of violence at some point in their careers. In several states, doctors have frequently gone on strike demanding stringent punishments for those who attack doctors.

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