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Dr k k Aggarwal Special

CMAAO Coronavirus Facts And Myth Buster: Metformin and COVID-19; High-titre plasma in hospitalized COVID-19 patients

Dr KK Aggarwal, President CMAAO, HCFI
18th January 2021
With input from Dr Monica Vasudev
1314: Metformin use is associated with reduced mortality in COVID-19 diabetics
Diabetes is an independent risk factor for COVID-19-related mortality; however, the risk is reported to be considerably reduced in patients taking metformin before the diagnosis of COVID-19. This raises the possibility that metformin may be protective in this high-risk population, suggest findings published in Frontiers in Endocrinology... Read more »
Dr k k Aggarwal

CMAAO Coronavirus Facts and Myth Buster: Ad26.COV2.S Vaccine

Dr KK Aggarwal, President CMAAO, HCFI
18th January 2021
Next in line in the armamentarium against COVID-19 is likely the single-dose Ad26.COV2.S vaccine, being developed by Johnson & Johnson/Janssen, anticipate infectious disease experts.
It got closer with promising interim phase 1/2a trial results that were published online January 13 in The New England Journal of Medicine. A single Ad26.COV2.S dose was found to be associated with S-binding and neutralizing antibodies in over 90% of the participants. The finding was evident in both adults aged 18-55 years and participants 65 years and older, as well as in participants given low-dose or high-dose vaccinations...Read more »
Dr k k Aggarwal

Association of liver protein and type 2 diabetes

18th January 2021Gastroenterology Hepatology Multispeciality
There is a substantial evidence depicting an association of high levels of the protein, called as fetuin-A, with insulin resistance. However, the role of fetuin-A, which is produced by the liver, in the development of diabetes is still unclear. The current study, published in The Journal of the American Medical Association conducted... Read more »

Hypertension Update

Dr k k Aggarwal

BPLTTC – Antihypertensive agents as risk modifiers for prevention of incident/recurrent CV events irrespective of baseline criteria: Placing amlodipine in context

18th January 2021 Hypertension
Hypertension, a prominent cause of premature mortality, affects 1.13 billion people worldwide, though blood pressure (BP)... Read more »
Zinc Update

Therapeutic options for acute cough due to upper respiratory infections in children

18th January 2021 Allergy & Immunology Multispeciality
An article published in Lung discussed that cough due to upper respiratory tract infections (URIs) is one of the most frequent complaints encountered by pediatric health-care providers and one of the most disruptive symptoms for children and families. Despite the frequency of URIs, there is limited evidence to support the few therapeutic... Read more »

News From All Specialities

India launches COVID-19 vaccination campaign, sanitation worker gets first shot

18th January 2021 Pulmonary Medicine Pathology & Lab Medicine
Sanitation worker Manish Kumar was the first in India to receive vaccination against COVID-19 on Saturday, as Prime Minister Narendra Modi launched one of the world’s largest COVID-19 immunization campaigns. Modi stated, “The disease separated people from their families, kept mothers away from their children,... Read more »

Rapid blood test to identify patients at highest risk of severe COVID-19

18th January 2021 Pathology & Lab MedicinePulmonary Medicine
Scientists have developed a rapid blood test that can predict within a day of hospitalization which patients with COVID-19 have the highest risk of severe complications or death. This could help identify the patients who may best benefit from specific investigational treatments. The test measures the levels of mitochondrial DNA... Read more »

Norway Warns of Vaccination Risks for Sick Elderly Patients

18th January 2021 Pathology & Lab MedicinePulmonary Medicine
Norway has stated that the COVID-19 vaccines may be risky for the very old and terminally ill. This is the most cautious statement yet that has come from a European health authority. Norwegian officials reported that 23 people had died in the country a short time after receiving their first dose of the vaccine... Read more »

CDC: New, contagious coronavirus variant could worsen pandemic

18th January 2021 Pathology & Lab Medicine Pharmacists
New, more contagious variants of coronavirus are likely to accelerate the spread of the virus, and the US should double down on efforts to protect people, stated the US Centers for Disease Control and Prevention. B.1.1.7, the variant first detected in Britain, is being found in the US as well, and modeling suggests that it could worsen the spread of the virus across the country,... Read more »

Childhood Insulin Levels Linked with Later Psychosis

18th January 2021 Psychiatry Pharmacists
A new study has shown a link between elevated insulin levels in childhood and psychosis in young adulthood. The analysis also showed an association between high childhood body mass index (BMI) and depression. The study, published online January 13 in JAMA Psychiatry, suggests that there might be a cardiometabolic signature... Read more »

Medicolegal Corner

Can a doctor disclose his patient’s information to the relatives?

18th January 2021
As per Medical Council of India Code of Medical Ethics Clause 7.14, “The registered medical practitioner shall not disclose the secrets of a patient that have been learnt in the exercise of his/her profession except -
i. in a court of law under orders of the Presiding Judge;
ii. in circumstances where there is a serious and identified risk to a specific person and/or community; ...Read more »

eMedi Humor

Is there another keyboard?

18th January 2021
Customer: My keyboard is not working anymore.
Tech support: Are you sure it’s plugged into the computer?
Customer: No. I can’t get behind the computer...Read more »

eMedi Quiz

Interscalene approach to brachial plexus block does not provide optimal surgical anesthesia in the area of distribution of which of the following nerves:

18th January 2021
1. Musculocutaneous.
2. Ulnar
3. Radial ...Read more »

Lifestyle Updates

eWellness: Honey excellent for cough

18th January 2021
A spoonful of honey can relieve night time cough in children and help them sleep better. In comparison with the cough syrup ingredient dextromethorphan or no treatment, honey seems better. According to a study published in the Archives of Paediatrics and Adolescent Medicine, the results are so strong that we can easily say that... Read more »

eSpiritual: How to remove negative thoughts

18th January 2021
Darkness is the absence of light and similarly, negative thoughts are absence of positive thoughts. The answer to negative thoughts is to bring back positive thoughts. An idle mind is the devil’s workshop and so, will always think negative. Here are some ways by which you can get rid of your negative thoughts:...Read more »

Inspirational: Going the Extra Mile

18th January 2021
A 20-year-old had just finished his first degree and asked for his father’s advice on how to approach the world of work. He had a long and distinguished career in the Army and had become commander–in–chief. He was a soldier’s soldier and his men adored him. He was strict and firm, but was very friendly...Read more »


Medical voice

Doctors Survey

Question 1 : Which of these courses would you pay for - You can select multiple options
How to modernize clinic
Growing your digitize you clinic and practice...
Medical voice

How Corona Aware Are You

Question 1 : How confident are you that you could recognize and respond to a potential coronavirus case?
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Moderately confident...


From Other Newsletter



Practical efficacy of olmesartan vs. azilsartan in patients with hypertension: MUSCAT-4 study

A randomized-controlled trial compared the practical efficacy of olmesartan with azilsartan in 84 patients treated with conventional ARBs for more than 3 months. These patients were randomly allocated to receive either 20mg of olmesartan (olmesartan medoxomil, OL group) or 20mg of azilsartan (azilsartan, AZ group)... Read more »



Exercise and Nutritional Intervention for Adults with Sarcopenic Obesity

People with sarcopenic obesity (SO) have both low muscle mass, i.e., sarcopenia, and high body fat, i.e., obesity. These individuals are at a greater risk of metabolic diseases and physical disability when compared with people with sarcopenia or obesity alone... Read more »


The skin microbiome: impact of modern environments on skin ecology, barrier integrity and systemic immune programming

An article published in the World Allergy Organization Journal elaborated on how the skin barrier structure and function are essential to human health. The authors stated that unrecognized functions of epidermal keratinocytes show... Read more »


An antibiofilm hydrofiber wound dressing: Clinical and in vitro performance

Biofilm has often been cited as a key pathological factor in non-healing wounds. It therefore seems crucial to manage the biofilm in order to expedite wound healing and achieve the desired outcome. A study by Scully and colleagues compared the clinical and in vitro performance... Read more »

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