Editor-in-Chief eMediNexus – Dr KK Aggarwal
17th November 2019

Air Pollution in Delhi and Harm Reduction: Even PM 2.5 reduction by 10 will help

Dr KK Aggarwal, Recipient of Padma Shri

  • Studies have consistently shown an association between elevated ambient levels of fine particulate matter (PM2.5) and increased mortality.
  • In a longitudinal study of the population of six United States cities followed for 14 to 16 years (mid-1970s through 1990), increased air pollution was associated with increased mortality; this increased mortality was most closely associated with the increase in fine particulate pollution (N Engl J Med. 1993;329(24):1753.)
  • A dose response was observed, with an increased mortality rate of 13 percent for every 10 mcg/m3 rise in PM2.5...read more

Mild side effects with single antidepressant dose of IV ketamine

Dr KK Aggarwal, Recipient of Padma Shri

(Excerpts from NIH, Nov. 15, 2019): National Institutes of Health researchers found that a single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression. Elia Acevedo-Diaz, M.D., Carlos Zarate, M.D., and colleagues at the NIH's National Institute of Mental Health (NIMH) report their findings in the Journal of Affective Disorders.

The researchers compiled data on side effects from 163 patients with major depressive disorder or bipolar disorder and 25 healthy controls...read more

Practice Updates

SIT as a promising and exciting approach to control dengue, chikungunya and Zika

The Sterile Insect Technique (SIT) successfully used to target insect pests that attack crops and livestock will now be tested as part of health sector to fight human diseases such as dengue, chikungunya and zika. The SIT involves rearing huge quantities of sterilized male mosquitoes in dedicated facilities, and then releasing them to mate with females in the wild. As no offspring is produced, the insect population reduces over time... read more

De-humanizing working conditions for sanitation workers need a push for change

According to a recent report, millions of sanitation workers are forced to work in conditions that endanger their health and lives, and violate their dignity and human rights. This report on the plight of sanitation workers in the developing nations is jointly authored by the International Labour Organization,... read more

FDA's approved Fetroja (cefiderocol) serves as additional therapeutic agent for cUTIs

Fetroja (cefiderocol), an antibacterial drug has been approved by the United States Food and Drug Administration (US FDA) for treatment of patients aged 18 years with complicated urinary tract infections (cUTIs), including kidney infections caused by susceptible Gram-negative microorganisms, who have limited or no alternative treatment options.... read more

PERSEVERE, a new biomarker-based tool to stratify pediatric patients at risk for sepsis

The development of the Pediatric Sepsis Biomarker Risk Model (PERSEVERE) assay may help in predicting septic shock outcomes and selecting early optimal treatment more precisely in kids. This test has been developed by Hector R. Wong, MD, director of critical care medicine at Cincinnati Children's Hospital Medical Center in Ohio, and colleagues over more than 10 years.... read more

Phase III trial finds a modified vaccine against smallpox non-inferior to the established vaccine

The trial performed in healthy US soldiers revealed that administration of modified vaccinia Ankara, or MVA, had immune responses comparable to established replicating-vaccinia, ACAM2000. The authors of this study stated that "A single MVA vaccination induced neutralizing antibody titers that were similar to those with ACAM2000 at day 14,.. read more

Electrocardiogram sensor in Apple watch series 4 and 5 is yet to convince cardiologists

The Apple Heart Study assessed the use of Apple Watch in detecting atrial fibrillation, a condition accompanied by high risk of stroke. The findings published in the New England Journal of Medicine indicates this type of passive monitoring to be effective, however, not everyone in the medical community,... read more

Medical Voice

Mexico is free from human rabies transmitted by dogs

(PAHO, Nov. 11, 2019):Mexico has become the first country in the world to receive validationfrom the World Health Organization (WHO) for eliminating dog-transmitted rabies as a public health problem. "Eliminating rabies doesn't happen by accident," said Dr Tedros Adhanom Ghebreyesus,... read more

IDEJ Update

Indian Diabetes Educator Journal (IDEJ), 1st of its kind in India aims to keep the members of diabetes care team abreast with concepts of DSME (Diabetes self-management education) and DSMS (Diabetes self-management support). IDEJ has set a new benchmark in educating the diabetes educators about evolving the concept of DSME- reaching to more than 25000 through Digital and Print Medium..... read more

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