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Editor-in-Chief eMediNexus – Dr KK Aggarwal
 
15th September 2018
Think before you prescribe
Knowledge of drug interactions may prevent undesirable clinical outcomes

Dr KK Aggarwal, Recipient of Padma Shri

Drug interactions occur when two drugs are taken at the same time and one drug affects the activity of the other drug resulting in an undesired clinical outcome in the form of either adverse effects or treatment failure or enhanced action of the other drug. Some drug interactions may even be potentially life-threatening. Drug interactions may also occur between drugs and food or between drugs and herbs.

Different drugs are absorbed differently. Some need to be taken without food i.e. on an empty stomach, while some drugs must be taken with food. Some drugs alter the absorption of the other drug by changing the pH. For example, concomitant administration of itraconazole capsules and proton pump inhibitors such as omeprazole or H2receptor antagonists such as famotidine and ranitidine impairs absorption of itraconazole resulting in decreased levels (Clin Infect Dis....read more

Top News

ICMR to analyze health records of Mahatma Gandhi

It may appear that Mahatma Gandhi, lean in physique and active in demeanor, was fit as a fiddle; but not many know he reeled under high blood pressure (BP). Gandhiji often used to fast, sometimes for periods stretching to 21 days, as a mark of rebellion in the tense political climate of the pre-independence era. At one such time, his blood pressure shot up to 180/110 mg/dL on the third day of his fast, says a note written by Sushila Nayar, former Health Minister, on March 5, 1939, in Rajkot, Gujarat. ... read more

Morning Medtalks

Morning MEDtalks with Dr KK Aggarwal 15th September 2018

The pelvic floor muscles aid control of your bladder and bowels. Strengthening these muscles can be helpful to people with stress incontinence as well as those with urge incontinence. This is done with Kegel exercises, which involve squeezing and releasing the muscles you use to hold in urine. A physical therapist can help you learn how to do the exercises properly. ... read more

Practice Updates

AHA new scientific statement on resistant hypertension

According to a new scientific statement from the American Heart Association (AHA) published September 13, 2018 in the journal Hypertension, resistant hypertension affects 12-15% of patients treated for high blood pressure. Patients are diagnosed with resistant HT when they need three or more medications to treat high BP but their BP still exceeds the goal... read more


Apple Watch gets FDA clearance for use in arrhythmia detection

The latest iteration of the Apple Watch, dubbed Series 4 gets FDA clearance for use in detection and notification of atrial fibrillation and other arrhythmias. It generates a single-lead ECG without any special band or third-party add-on. Instead, a user touches a finger to electrodes built into the crown and a new electrical heart rate sensor in the back crystal provides the other contact... read more


A new injectable drug for treatment of hairy cell leukemia

The US Food and Drug Administration (FDA) has approved Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell leukemia (HCL) who have received at least two prior systemic therapies, including treatment with a purine nucleoside analog.... read more


Use of inhaled steroids increases risk of nontuberculous mycobacteria pulmonary infections

Use of inhaled corticosteroids, particularly use of high dose inhaled corticosteroids and long-term use was associated with 2.7 times increased risk of nontuberculous mycobacteria pulmonary infections, according to new research published online September 14, 2018 in the Annals of the American Thoracic... read more


Study supports earlier & narrower age range for lacrimal duct probing in congenital nasolacrimal duct obstruction

As per a study published online August 30, 2018 in JAMA Ophthalmology, probing the lacrimal duct of a child with congenital nasolacrimal duct obstruction between age 9 and 15 months may be reasonable given that the rate of spontaneous resolution plateaued after 9 months and initial probing success declined after 15 months.... read more

eMedi Humor
Medicolegal Corner
eMedi Quiz
a. Hematuria
b. Weight loss
c. Increased urine output
d. Increased blood pressure
Lifestyle Updates
 
Inspirational Story 1: The Trouble Tree
Inspirational Story 2: Height of perfection
Timely preventive health checkups a must to avoid kidney diseases
People with existing risk factors or health complications should be careful
 
New Delhi, 14 September 2018: As per a recent study, people with acute critical illness and no prior kidney disease have an increased risk of kidney complications and related mortality. Those who had experienced acute kidney illness were at an increased risk of renal complications, developing chronic kidney disease and then end-stage kidney disease, with septicemia and septic shock being the strongest risk factors. It is imperative to get kidney functions checked in a timely manner, especially in those with some pre-existing health conditions.

Chronic kidney disease or CKD is characterized by a gradual loss of kidney function over time and may eventually lead to kidney failure, causing patients to undergo dialysis or a kidney transplant. The signs and symptoms are not noticeable until the disease is fairly well advanced and the condition has become severe. By this time, most of the damage is irreversible.

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