Editor-in-Chief eMediNexus – Dr KK Aggarwal
15th February 2019
Should cannabis (Bhang) be used as a medicine? The answer lies in more scientific research

Dr KK Aggarwal, Padma Shri Awardee

Recently, the scientific community is focusing on the possible medical uses of cannabis.

Many states in the United States have legalized marijuana for medical purposes. It may potentially help fight the opioid epidemic due to their use in chronic pain. In India, Bhang is not restricted under the Narcotics Act.

Cannabis leaves-based drugs were found to be effective in alleviating pain and other symptoms in cancer patients after chemo- and radiotherapy in a pilot study conducted in 2018 by Central Council For Research in Ayurvedic Sciences (CCRAS), a research body under the Ministry of AYUSH in collaboration with the Gujarat Ayurved University, Jamnagar on cancer patients undergoing treatment at the Tata Memorial Hospital in Mumbai....read more

MRI-guided treat-to-target strategy in RA patients in remission not superior to conventional treat-to-target strategy

Dr KK Aggarwal, Padma Shri Awardee

Using MRI-guided treat-to-target strategy did not improve the rate of disease activity or reduce radiographic progression compared with a conventional treat-to-target strategy in patients with rheumatoid arthritis in clinical remission, reports a new JAMA study, online Feb. 5, 2019.

The 2-year multicenter IMAGINE-RA trial randomized patients with RA in clinical remission, to either MRI-guided treat-to-target strategy or conventional treat-to-target strategy. Results showed that 85% vs 88%, respectively, reached the primary clinical end point (absence of MRI bone marrow edema combined with clinical remission,....read more

Practice Updates

Exposures to drug-resistant brucellosis in the US linked to raw milk

The Centers for Disease Control and Prevention and state health officials are investigating potential exposures to Brucella strain RB51 (RB51) in 19 states, connected to consuming raw (unpasteurized) milk from Miller’s Biodiversity Farm in Quarryville, Pennsylvania. One case of RB51 infection (brucellosis) has been confirmed in New York, and an unknown number of people may have been exposed to RB51 from drinking the milk from this farm.... read more

USPSTF recommends counseling for women at high risk of perinatal depression

The US Preventive Service Task Force (USPSTF) has recommended that clinicians provide or refer pregnant and postpartum persons who are at increased risk of perinatal depression to counseling interventions (B recommendation) in a final recommendation statement published in JAMA... read more

Pembrolizumab + axitinib improves overall survival and progression-free survival in metastatic renal cell carcinoma

Results from the randomized, phase III KEYNOTE-426 clinical trial show that first-line therapy with a combination of the PD-1 targeted immunotherapy pembrolizumab and the VEGF-targeted tyrosine kinase inhibitor axitinib extended both overall survival and progression-free survival for patients with clear-cell metastatic renal cell carcinoma (mRCC), compared with the current standard of care, sunitinib.... read more

Hearing impairment associated with greater risk of cognitive decline

Hearing impairment is associated with accelerated cognitive decline with age, though the impact of mild hearing loss may be lessened by higher education, according to a study published in the February 12, 2019 issue of the Journal of Gerontology: Series A Medical Sciences. Those with more serious hearing impairment showed worse performance ...read more

Patients with hidradenitis suppurativa at a greater risk of developing lymphoma

Patients with hidradenitis suppurativa are at a greater risk of developing lymphoma compared to those who do not have hidradenitis suppurativa. The prevalence of non-Hodgkin lymphoma (NHL) was 0.40% among individuals with and 0.35% among those without HS; the prevalence of Hodgkin lymphoma ... read more

PumpStart: Teaching CPR to high school students

In a study reported in the Journal of Education, participants in the PumpStart program showed significant improvements in CPR technique and confidence in acquired skills for both the pilot semester... read more

Medical Voice

Smoking Tobacco Doubles Risk of Recurrent Tuberculosis

Patients who continue tobacco smoking after successful treatment of TB often develop TB again called recurrent TB.
In a study published in April 2014 issue of the International Journal of Tuberculosis and Lung Disease theresearchers followed a large sample of fully treated 5,567 bacteriologically confirmed TB patients in Taiwan. ... read more

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Lifestyle Updates
Inspirational Story 1: A Touching Story from a Father
Inspirational Story 2 : Temper Control
Beware of drinks spiked with date rape drugs this Valentine’s Day
A little vigilance and precaution can avert a major crisis
New Delhi, 14 February 2019: The Food and Drug Administration (FDA) is keeping a high vigil on date rape drugs during the week of Valentine’s Day. Wholesalers and retailers have been instructed about regulating the sale. Although alcohol, marijuana, ecstasy, over-the-counter sleeping pills and anti-histamines, and even cold medications can be used, the term applies to any of the three drugs: GHB (gamma hydroxybutyric acid), Rohypnol (flunitrazepam), popularly called “Roofies” and ketamine (ketamine hydrochloride).

Rohypnol is legal in Europe and Mexico but is banned in the US and India. In 2013, ketamine hydrochloride was shifted from Schedule H to Schedule X of the Drugs & Cosmetics Rules to prevent its easy availability and misuse. It has been listed as psychotropic substance under the Narcotic Drugs and Psychotropic Substances (NDPS) Act.

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