Editor-in-Chief eMediNexus – Dr KK Aggarwal
14th February 2019
Prescribing empirical and broad-spectrum antibiotics

Dr KK Aggarwal, Padma Shri Awardee

The use of antibiotics in day to day practice for the patient with community-acquired or hospital-acquired infections is often empirical, as the results of culture and sensitivity or specific diagnostic tests are still awaited. This is especially true for infections in critically ill patients where the urgency of situation demands empirical treatment.

Broad spectrum antibiotics are typically selected for empiric therapy as the aim is to cover as many etiopathogens as possible that are usually associated with that particular clinical presentation. They are initiated as soon as specimens are collected....read more

Updated EULAR guidelines: Avoid DMARDs in patients with hand osteoarthritis

Dr KK Aggarwal, Padma Shri Awardee

The European League Against Rheumatism (EULAR) has published updated guidelines for the management of hand osteoarthritis (OA).

The guidelines, published in January 2019 issue of Annals of the Rheumatic Diseases give emphasis to shared decision-making and multidisciplinary and multimodal treatment. They also advise against using disease-modifying antirheumatic drugs (DMARDs) given their lack of efficacy in hand OA.....read more

Practice Updates

New WHO-ITU standard aims to prevent hearing loss among 1.1 billion young people

Nearly 50% of people aged 12-35 years – or 1.1 billion young people – are at risk of hearing loss due to prolonged and excessive exposure to loud sounds, including music they listen to through personal audio devices. The World Health Organization (WHO) and the International Telecommunication Union (ITU) have issued a new international standard for the manufacture and use of these devices,... read more

More than 9,000 infected with Swine flu across the country

Death toll across the country due to swine flu has soared to 312 with the number of deaths in the last week recorded at 86, according to data released by the Union Health Ministry on Monday. Over 9,000 persons have so far been affected by the H1N1 virus, with Rajasthan still topping the list with highest number of cases and deaths, according to the data.... read more

BP variability indicative of poor prognosis post-stroke

According to a new study presented at the American Stroke Association's International Stroke Conference in Honolulu, patients with more variation in their systolic blood pressure, the top number in the measurement, had a higher risk of death within 90 days.... read more

Inexpensive supplement for women increases infant birth size

For women in resource-poor settings, taking a certain daily nutritional supplement before conception or in early pregnancy may provide enough of a boost to improve growth of the fetus, according to the multi-country Women First trial published Feb. 5, 2019 in the American Journal of Clinical Nutrition. The supplement consists of dried skimmed milk,...read more

Omadacycline noninferior to linezolid as treatment of acute bacterial skin and skin-structure infections

Omadacycline, an aminomethylcycline antibiotic was noninferior to linezolid for the treatment of acute bacterial skin and skin-structure infections in terms of clinical response and had a similar safety profile, according to a study published Feb. 7, 2019... read more

Radiolabeled PSMA-targeted treatment improves survival in in men with metastatic prostate cancer

A single-arm, phase II trial in men with PSMA-positive metastatic, castration-resistant prostate cancer (mCRPC) that progressed despite standard therapies, found that in the majority of men, the cancers were responsive to treatment with a novel, targeted radiation therapy called Lutetium-177 PSMA-617 ... read more

Medical Voice

Flu vaccine shortage: Can I take half the dose?

Half-dose flu vaccine has been shown to demonstrate a similar effectiveness to full-dose vaccine measured by the number of diagnoses of influenza and symptom survey of participating health care workers. Administration of half-dose TIV is an acceptable strategy for maximizing the number of vaccinations in health care workers,... read more

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Lifestyle Updates
Inspirational Story 1: Temper Control
Inspirational Story 2: If and When
Reduce harm to the heart and overall health by reducing dietary salt intake
People with hypertension should consume not more than 6 g of sodium chloride/day
New Delhi, 13th February 2019: Studies indicate that high salt intake can have detrimental effects on blood pressure. Over time, this can lead to hypertension and cardiovascular diseases. To lower the risk of developing a heart disease by 25% and that of mortality due to this by 20%, it is imperative to restrict dietary intake of salt. It is therefore an effective harm reduction strategy as also discussed in the first-ever harm reduction conference organized by the HCFI and IJCP on 30th January 2019 at the India Habitat Centre, New Delhi.

As per recent figures by the Public Health Foundation of India (PHFI), salt intake among Indian adult Indians is high. It exceeds the levels recommended by the WHO.

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