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Dr K K Aggarwal

Dr KK Aggarwal
Dr BC Roy Awardee
Sr Physician and Cardiologist
Moolchand Medcity
President, Heart Care
Foundation of India
Gp Editor-in-Chief,
IJCP Group
Delhi Medical Council
Director, IMA AKN Sinha Institute (08-09)



14th November Saturday 

Dear Colleague,

Today is world Diabetes day
Treating diabetes is a challenge that clinicians confront everyday. It is a difficult subject yet easy to learn. We have compiled sone basic rough easy to learn formulae for the same.

Formula of 80
Keep fasting blood sugar <80 mg%
Keep the lower BP <80 mmHg
Keep LDL cholesterol <80 mg%
Keep abdominal girth <80 cm
Keep resting pulse <80/minute
Keep HDL cholesterol >40 (half of eighty)
Keep TGs <160 mg% (double of eighty)
If fasting sugar is between 80 and 160 (80x2), try lifestyle change and/or metformin
If blood sugar is between 160 (80x2) and 240 (80x3), you may need two drugs
If blood sugar is between 240 (80x 3) and 320 (80x 4), you may need three drugs or two drugs with insulin
If blood sugar is >320 mg% (80x4 ), you may need insulin with or without oral drugs
Formula of 3
For insulin start 0.3 units/kg body weight
For moderate cases you can start 0.6 units/kg body weight (0.3 x 2)
For obesity one can start with 0.9 units/kg body weight (0.3 x 3)
Increase by three units every third day
Do A1C every three months
Start insulin if three drugs fail
1500 formula

Dividing 1500 with the total daily insulin dose will provide the change in blood sugar levels with one unit of insulin.
500 formula

Dividing 500 with total daily dose of insulin will give the grams of carbohydrates required to neutralize one unit of insulin.


Dr K K Aggarwal



FDA updates label for diabetes drug citing risk of kidney problems

The US FDA advised has health care professionals of revisions to the prescribing information for Byetta (exenatide) to include information on postmarketing reports of altered kidney function, including acute renal failure and insufficiency.


The following recommendations were included in the revisions to the product label:

1. Byetta should not be used in patients with severe renal impairment (creatinine clearance values of <30 mL per min) or end-stage renal disease.

2. Caution should be applied when initiating or increasing doses of Byetta from 5 g to 10 g in patients with moderate renal impairment (creatinine clearance values of 30-50 mL per min).

3. Patients receiving Byetta should be carefully monitored for the development of kidney dysfunction, and the continued need for Byetta should be reevaluated if a suspicion of kidney dysfunction arises.

4. Patients should be provided with the Byetta Medication Guide when they receive their prescription to aid in understanding the benefits and potential risks associated with Byetta use.

On October 30, 2009, the US FDA approved an expanded indication for Byetta (exenatide) injection, as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Byetta is not indicated for use in type 1 diabetes, or diabetic ketoacidosis.

To stay healthy, drink eight cups of tea daily

A new expert report states that drinking at least 8 cups of tea daily may help one to lead a long and healthy life. According to Dr Carrie Ruxton, a nutrition expert, caffeine in drinks can decrease the chances of stroke and heart attacks and also makes the drinkers more attentive and cheerful and thus enhancing their brain power. Results of 47 independent studies were compared. The optimum caffeine intake was 400mg in a day for an adult, which corresponds to eight cups of tea or four coffees. In children, the limit should be 95mg a day, which means the same as two small cups of tea or one small, weak coffee

India's first prequalified H1N1 drug launched by Cipla

Cipla Ltd. has launched the generic version of oseltamivir under the name of Antiflu to treat the H1N1 flu. Antiflu will be priced at Rs 475 for 10 capsules, with 75 ml syrup to cost the same to be sold only on a doctor's prescription. Antiflu is the only flu medicine from India to be pre qualified for H1N1 flu by the WHO.

A new test may diagnose early Alzheimer's

A new multi-tasking test, developed by scientists at Edinburgh University, can help make a distinction between symptoms of depression and early Alzheimer's. Individuals with early Alzheimer's disease have impaired reasoning and memory that can be erroneously attributed to depression. This delays crucial treatment.  The study subjects were asked to carry out two tasks at the same time. The 'dual-tasking' ability of 89 Alzheimer's patients, individuals with chronic depression and healthy elderly individuals with no memory impairment were compared in a study. The study results showed that people with Alzheimer's fared much worse compared to the other two groups. The study is published in the Journal of Neurology.

Using Cell phone while walking causes inattentional blindness

In a study, US scientists have concluded that cell phone users, while they are simultaneously on phone and walking, experience inattentional blindness even for simple activities. This is the effect of divided attention. Participants were grouped on the basis of whether they were walking while talking on cell phone or listening to MP3 player, walking without any such electronic items or walking in a pair. Mobile phone users walked unhurriedly, changed directions more often and also were less likely to recognize other people. Individuals who used cell phones while walking also did not much notice any unusual activity along their path.

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 A new diagnostic test to detect Early Dengue fever

A new ELISA test called the Platelia (tm) dengue NS1 Ag Assay is now available in India. The kit aims to help diagnose dengue on the very first day of symptoms. This new test detects the dengue virus NS1 antigen as soon as the first clinical signs appear allowing for rapid and early diagnosis. While, the currently available serological tests for dengue can identify the dengue virus only 4-6 days after the appearance of the first symptoms indirectly by detecting antibodies. NS or nonstructural protein is a glycoprotein which has no established biological activity, but is important for viability of the virus. Early diagnosis is crucial to initiate appropriate line of management at the earliest.

Colchicine now FDA-approved for prophylaxis of gout flares

Colchicine received FDA approval for the prophylaxis of gout flares. It has earlier been FDA approved for the treatment of acute gout flares. 

Monoclonal antibody Arzerra for refractory chronic lymphocytic leukemia granted FDA approval

Arzerra (ofatumumab) received accelerated approval by the FDA on October 26, 2009 for the treatment of patients with chronic lymphocytic leukemia (CLL) whose disease has been refractory to treatment with fludarabine and alemtuzumab. Arzerra is a monoclonal antibody that provokes an immune response against normal and malignant B cells. It attaches to small and large loop epitopes on CD20, a protein molecule found on the surface of B cells that become cancerous in CLL.

X ray machine crowned the greatest scientific invention

In a poll conducted by the Science Museum in London to commemorate its centenary, X-ray machine was voted as the best invention that had the greatest impact on the past, present and future. Discovery of penicillin and the double-helix structure of DNA were the next on the list. A German physicist Wilhelm Rontgen first discovered X-rays in November 1895. Following the discovery of x-rays, the x-ray machine was developed by John Reynolds and Russell Reynolds, a father and son duo.

1. X ray machines
2. Penicillin
3. DNA double helix
4. Apollo 10 capsule
5. V2 Rocket Engine
6. Stephenson's Rocket
7. Pilot ACE Computer
8. Steam Engine
9. Model T Ford
10. Electric Telegraph

Good news...a healthy ice cream on the way

Scientists at the University of Missouri are working to create a healthy ice cream. The researchers are trying to add nutrients like dietary fiber, antioxidants and probiotics to the new healthy ice cream making it another functional food. Functional foods have health benefits that go beyond simple nutrition. According to Ingolf Gruen, professor of food chemistry and ice cream researcher in the College of Agriculture, Food and Natural Resources, these ingredients were selected because of their familiarity to the customers and also they have established health benefits. A prototype ready for tasting may be ready within six months.

John Crofton, the pioneer of TB cure

Sir John Crofton passed away in Edinburgh at the age of 97 years on 3rd November. Amongst his vast body of work, perhaps the most notable is developing effective treatment for pulmonary tuberculosis. His research transformed treatment of TB, then the scourge of millions across the world and saved several lives. He along with his team found a cure for TB by using a combination of three antibiotics, streptomycin, para-amino salicylic acid (PAS) and isoniazid, the 'Edinburgh Method'.


Converting Blood Glucose Levels

Multiply the mmol/L by 18 to get mg/dL (or divide with 0.055).
Divide the mg/dL by 18 to get mmol/L (or multiply by 0.055).

Words of wisdom...

Let food be thy medicine, and let thy medicine be food...Hippocrates

A wise man should consider that health is the greatest of human blessings, and learn how by his thought to derive benefit from his illnesses... Hippocrates

Medicine is a science of uncertainty and an art of probability...Sir William Osler


The surgeon told his patient who woke up after having been operated: "I'm afraid we're going to have to operate you again. Because, you see, I forgot my rubber gloves inside you." "Well, if it's just because of them, I'd rather pay for them if you just leave me alone."

"Would it hurt to play Ping-Pong on a full stomach?" Arthur asked his doctor. "Well," the doctor replied, "I think a table would make more sense."

The Art of Management

  •  Never take a problem to your boss unless you have a solution.
  •  The best way to kill an idea is to take it to a meeting.
  •  Friendship founded on business is always better than business founded on friendship.
  •  You won't get a second chance to make the first impression.

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 emedinews: revisiting 2009

IJCP Group is organizing emedinews: Revisiting 2009, a day -long conference on 10th Jan  2010 at Maulana Azad Auditorium. It will be attended by over 1000 doctors. Topics will be top happenings in the year 2009. There is no registration fee however advanced registration is required.  Top experts will deliver lectures. CME will be followed by lively cultural evening, doctors of the year award, dance and dinner. For regiatration mail  emedinews@gmail.com. We have crossed 550 registrations in 3 days.  

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