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  From the Desk of Editor–in–Chief
Dr KK Aggarwal

Padma Shri and Dr B C Roy National Awardee
Dr KK Aggarwal
President, Heart Care Foundation of India; Sr Consultant Physician, Cardiologist and Dean Medical Education Moolchand Medcity; Chairman Ethical Committee Delhi Medical Council; Chairman (Delhi Chapter) International Medical Sciences Academy; Hony Director IMA AKN Sinha Institute (08–09); Hony Finance Secretary National IMA (07–08); Chairman IMA Academy of Medical Specialties (06–07); President Delhi Medical Association (05–06), President IMA New Delhi Branch (94–95, 02–04); Editor in Chief IJCP Group of Publications & Hony. Visiting Professor (Clinical Research) DIPSAR


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  Editorial …

11 th December 2011, Sunday

NSAIDs and Miscarriage

Exposure to NSAIDS during pregnancy may increase the risk of miscarriage.

A large study using data from a Canadian registry found exposure to non salicylate NSAIDs during the first 20 weeks of pregnancy, including both nonselective and COX–2 selective drugs, was associated with an increased risk of miscarriage.

CMAJ 2011;183:1713.

For More editorials…

Dr KK Aggarwal
Group Editor in Chief

  eMedinewS Audio PostCard

Padma Shri and Dr BC Roy National Awardee Dr KK Aggarwal on 63rd CSI Live Coverage

Dr KK Aggarwal in conversation with Dr Jagat
Narula on Future Imaging

Audio PostCard
    Photo Feature (from the HCFI Photo Gallery)

18th MTNL Perfect Health Mela: Medico Masti – An Inter College Health Festival

Infotainment is a new concept of creating health education where education is inter linked with entertainment.

Dr K K Aggarwal
    National News

Kerala kids to get new pentavalent vaccine shots

As part of the Universal Immunisation Programme of the Indian government, Kerala will Dec 14 introduce the pentavalent vaccine which provides protection to a child from five life–threatening diseases. "In a year, 5.5 lakh kids in the state would have received a shot of this vaccine," Rajiv Sadanandan, principal secretary in the state’s health department, told reporters here Tuesday at an interaction with the media ahead of the launch of the vaccine in the state. The vaccine provides protection from diphtheria, pertussis, tetanus, hepatitis B and haemophilus influenza type B (HiB). The pentavalent vaccine will replace the current hepatitis B and DPT primary vaccines schedule in the immunisation programme. (Source: http://news.bioscholar.com/2011/12/kerala–kids–to–get–new

For comments and archives

Kindly visit Facebook for CSI News. It will cover minute to minute happenings of the 63rd CSI conference at Mumbai 8–11th December

For comments and archives

Certificate courses in 2D and 3D Echocardiography/Fellowship Diploma in non invasive cardiology: Contact Dr KK Aggarwal, Moolchand Medcity, email: emedinews@gmail.com

    International News

Short–Term TB Combination as Successful as Isoniazid Therapy

Weekly rifapentine plus isoniazid given under direct supervision for 3 months was as effective in preventing tuberculosis (TB) as 9 months of daily self–administered isoniazid, according to a report published in the December 8 issue of the New England Journal of Medicine. During the 33 months after therapy, 7 of 3986 high–risk adult participants (0.19%) in the combination rifapentine–isoniazid treatment group developed culture–confirmed TB compared with 15 of 3745 (0.43%) patients who only received isoniazid (P<.001) in an open–label, randomized, noninferiority trial. The researchers found that 2.7% of the patients in the isoniazid treatment group discontinued therapy because of hepatoxicity compared with 0.4% of patients in the combination therapy group.

Source: http://www.medscape.com/viewarticle/754948

For comments and archives

Huge’ Development in HER2+ Metastatic Breast Cancer

The results of CLEOPETRA, a new study of HER2–positive metastatic breast cancer in the first–line setting, published online December 7 in the New England Journal of Medicine and which will be presented at the 34th Annual San Antonio Breast Cancer Symposium showed that the combination of trastuzumab and the experimental agent pertuzumab significantly prolonged progression–free survival (PFS) by 6 months compared with trastuzumab alone. All 808 women in the phase 3 study also received docetaxel. Because pertuzumab and trastuzumab have complementary mechanisms of action and bind at different epitopes, the combination of the 2 agents provide a "more comprehensive blockade of HER2 signaling and result in greater antitumor activity than either agent alone." Source: http://www.medscape.com/viewarticle/755023

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Women on Night Shift Have Increased Risk for Type 2 Diabetes

Women who worked irregularly scheduled night shifts had up to a 60% higher risk of developing type 2 diabetes than women who worked only day and evening hours, according to a study, published online December 6 in PLOS Medicine. An Pan, PhD, a research fellow in the Department of Nutrition at the Harvard School of Public Health, Boston, Massachusetts, the chief investigator of the study, used prospective data collected over the course of 18 to 20 years on 177,184 women aged from 25 to 67 years in the Nurses’ Health Study and found that women who had worked rotating night shifts at least 3 times per month for 1 to 2 years had a 5% increased risk of developing type 2 diabetes. The risk rose the longer a woman had done rotating night–shift work, from 20% after 3 to 9 years to almost 60% for 20 or more years.

For comments and archives

    Cardiology eMedinewS

(Dr KK Aggarwal, Group Editor in Chief, IJCP Group of Publications and eMedinews)

63rd CSI conference at Mumbai 8–11th December. Grab your ecopy of happenings of 10th December Conference.

Conference e-Newsletter

Presidential lecture: We should practice ethics in cardiology: Dr S Mathew

Read More

The End Stage Heart Disease

Read More

Why And When To Support The Failing Heart

Read More

Extracorporeal mechanical circulatory assist/Tandem Heart

Read More

    Twitter of the Day

@DrKKAggarwal: The holiday season is also the season for heart attack.

@DeepakChopra: Manhattan–20111209–00573.jpg Good Morning from NYChttp://twitpic.com/7qt3kt

    Spiritual Update

(Dr KK Aggarwal, Group Editor in Chief, IJCP Group of Publications and eMedinews)

Mourning: A Healing Touch

The reference to grieved mourning a death can be found in the Vedic literature. There is custom that the grieved partner is made to weep till she or he is overwhelmed with emotions. In fact all relatives and friends participate in the exercise, depending upon their respective closeness to the deceased.

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    An Inspirational Story

(Ms Ritu Sinha)

The Last Game

Wow! What a ride! I feel like I just got off the worlds biggest rollercoaster and I am still woozy! I don’t know to laugh or cry. I feel a sense of relief, yet disappointment. I even dream to jump back on. I dare not for my heart may not take another ride!

My son started football as a freshmen boy, and now four years later, a senior, played his last game. He has learned a lot about life; the ups and downs that come without warning. He’s learned life isn’t always fair. Sometimes you watch life "happen" for others, while on the sidelines wondering what’s wrong with me. The sweat and tears. Oh the tears…if I had a bottle to catch them all! Tears of joy, disappointments, dropped balls, what ifs, only ifs, the injury’s. The list goes on and on.

My mind wanders back over the years to my own tears and emotions.

In two hours time I was capable of love, hatred, excitement, disappointment and great anxiety! I was a mom all week packing lunches, carpooling, cooking and breaking up fights before school, after school and at the dinner table! Trying to make the home a safe haven for our kids!! ON Friday nights I turned into a screaming, poor sported fan, full of pride.

The first time I sat at a game and screamed I looked around to see who it was, I couldn’t believe that noise came out of my mouth. And so it was my glorious life for four years. Cool aid mom during the week and crazy, screaming fan on Friday nights! A couple times I even thought I’d make a great coach! I always knew what the coach should have done after the play was over!

I ask myself, "Would I do it again?" The answer is most assuredly a YES. I’d do it again and again and again and again! I will never forget the last game. The kids all squished together in a circle of unity, chanting, swaying back and forth holding their helmets up high into the sky. ON this night it came clear to me it wasn’t about any one player or position. It didn’t matter who started or ended or just watched from the sidelines. This was a family. Sometime, somewhere and somehow, along the way, they became ONE.

For comments and archives

    Fitness Update

(Contributed by Rajat Bhatnagar, International Sports & Fitness Distribution, LLC, http://www.isfdistribution.com)

Consumption Of Processed Meats Associated With Prostate Cancer

Increased consumption of ground beef or processed meat is positively associated with aggressive prostate cancer, according to a study published in the online journal PLoS ONE.

The research team, led by John Witte of University of California, San Francisco, also found that the correlation was primarily driven by red meat that was grilled or barbequed, especially when well done.

They suggest that this result, which was determined based on the meat consumption habits of about 1,000 male participants, is due to increased levels of carcinogens in meat prepared these ways. The report furthers previous findings of the correlation between meat consumption and prostate cancer, and may help determine particular compounds that could be targeted for prostate cancer prevention.

For comments and archives

    Healthy Driving

(Conceptualized by Heart Care Foundation of India and Supported by Transport Department; Govt. of NCT of Delhi)

The standard required for driving is the ability to read a car number plate at 20 meters.

    Medicine Update

(Dr. Neelam Mohan, Director Pediatric Gastroenterology, Hepatology and Liver Transplantation, Medanta)

What is functional constipation?

Functional or idiopathic constipation is mainly caused by the painful bowel movement with resultant voluntary withholding of feces to avoid unpleasant defecation. Because of prolonged stasis of stools in the rectum, the fluid is absorbed and hard fecoliths are formed, which are very difficult for the child to bring out so resulting in more pain and the child trying to hold the stools further. Thus a vicious cycle sets in. Eventually, liquid stool from the proximal colon may percolate around hard retained stool and pass per rectum involuntarily (encopresis or fecal soiling). In fact, almost 30–50% children with functional constipation develop encopresis.

Causes of initial painful defecation: Change in routine or diet, stress, illness, child’s postponing defecation because he or she is too busy (morning school), forceful toilet training, exposure to antimotility drugs (antispasmodic, antidiarrheal, antitussive etc).

For comments and archives

    IJCP Special

Dr Good Dr Bad

Situation: A patient developed asthma within a year of menopause.
Dr. Bad: It is not asthma.
Dr. Good: It is associated with menopause.
Lesson: The onset of asthma within a year of menopause is a separate asthma phenotype.

For comments and archives

Make Sure

Situation: A patient with chest pain with normal ECG died half an hour later.
Reaction: Oh my God! Why was acute MI not suspected?
Lesson: Make sure all patients of chest pain are observed for 12 hours. ECG can be normal in acute heart attack for up to six hours.

For comments and archives

    Quote of the Day

(Dr GM Singh)

Make it thy business to know thyself, which is the most difficult lesson in the world. – Miguel de Cervantes

    Lab Update

(Dr Arpan Gandhi and Dr Navin Dang)

Platelet count

Thrombocytopenia (or low platelet count) is divided pathophysiologically into production defects and consumption defects based on examination of the bone marrow aspirate or biopsy for the presence of megakaryocytes.

  • Production defects are seen in Wiskott–Aldritch syndrome, May–Hegglin anomaly, Bernard–Soulier syndrome, Chediak–Higashi anomaly, Fanconi’s syndrome, aplastic anemia, marrow replacement, megaloblastic and severe iron deficiency anemias, uremia, etc.
  • Consumption defects are seen in autoimmune thrombocytopenias (including ITP and systemic lupus), DIC, TTP, congenital hemangiomas, hypersplenism, following massive hemorrhage, and in many severe infections.

For comments and archives

    Mind Teaser

Read this…………………

What do the words ALMOST and BIOPSY have in common

Yesterday’s Mind Teaser: A patient had the following echo findings

d MV = 4 cm, d LVOT = 2.5 cm, TVI MV = 4 cm, TVI LVOT = 25 cm, V Ao = 2.5

This patient should have: a) Absent A2; b) Opening snap; c) Quincke’s pulse; d) Large V–wave; e) Clubbing

Answer for Yesterday’s Mind Teaser: A (MV) × TVI (MV) – A (LVOT) × TVI (LVOT)
= 50.2 < 122.6
= 72 mL
Inflow < Outflow: AR
RV > 60 = Severe AR
Answer: c

Correct answers received from: Dr Prabha Sanghi, Dr KV Sarma, Raju Kuppusamy, Dr Chandresh Jardosh, Dr Jainendra Upadhyay, Dr Jatin, Dr RS Sharma, Dr Pritam, Dr Sachin.

Answer for 9th December Mind Teaser: Regurgitant Volume = A(MV) × TVI(MV) – A(LVOT) × TVI(LVOT)
Correct answers received from: Dr Sahahsi, Dr Priya, Dr Uma, Dr Krishna,
Dr Manju.

Send your answer to ijcp12@gmail.com

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   Laugh a While

(Dr GM Singh)

An anesthesiologist is a doctor who works in the operating room to delay your pain until such time as you get his bill.

    Medicolegal Update

(Dr Sudhir Gupta, Additional Prof, Forensic Medicine & Toxicology, AIIMS)

Facilitate cadaver organ retrieval for transplantation

In India, certain amendments to the Human Organ Transplant Act 1994 are required to enhance cadaver organ retrieval and transplantation to bridge the huge demand–supply gap. The pool of donors, including increasing the supply of organs by widening the definition of ‘near relatives’ by allowing organ swaps among needy families, as well as, simplifying cadaver transplant procedures. The paired matching should be permitted i.e. if patient A’s donor does not match A, and likewise for patient B, then donor switch should be allowed, if it results in a match. Swaps or exchanges between families unable to fulfill the need of their family member in need of a transplant.

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    Public Forum

(Press Release for use by the newspapers)

Get your Press release online http://hcfi.emedinews.in (English/Hindi/Audio/Video/Photo)

Avoid Smoking in winter

Smoking can not only precipitate heart attack, paralysis and increase blood pressure but can also increase the risk of erectile dysfunction in men. Men who smoke 20 cigarettes a day are 40% more likely to struggle with erectile dysfunction than men who do not smoke, said Padma Shri & Dr. B.C. Roy National Awardee, Dr. KK Aggarwal, President, Heart Care Foundation of India.

Nicotine present in smoke can constrict the blood supply to various organs. As per a study published in the journal Tobacco Control in men aged 16–59 the risk of erectile dysfunction is almost double in smokers than in non smokers. Apart from smoking, obesity, heavy alcohol consumption and misuse of Viagra like drugs can also disturb men’s sexual health.

Apart, uncontrolled diabetes, blood pressure, which is common in winter season also add to the same.

Depression is also common in winter adding to the agony. For those who want to quit smoking winter is the best time to do so.

For comments and archives

    Readers Responses
  1. Dear Sir, Thanks for the CSI Updates. Regards: Dr Priya
    Forthcoming Events

CSI 2011

63rd Annual Conference of the Cardiological Society of India

Date: December 8–11, 2011.
Venue: NCPA Complex, Nariman Point, Mumbai 400021

Organizing Committee

B. K. Goyal – Patron
Samuel Mathew – President CSI
Ashok Seth – President Elect & Chairman Scientific Committee
Lekha Adik Pathak – Chairperson
Satish Vaidya & C. V. Vanjani – Vice Chairman
N. O. Bansal – Organizing Secretary
B. R. Bansode – Treasurer
Ajit Desai, Ajay Mahajan, G. P. Ratnaparkhi – Jt. Org. Secretaries
Shantanu Deshpande, Sushil Kumbhat, Haresh Mehta – Asst. Org. Secretaries
D. B. Pahlajani, A. B. Mehta, M. J. Gandhi, G. S. Sainani, Sushil Munsi, GB Parulkar, KR Shetty – Advisory Committee

Contact: Dr. Lekha Adik Pathak, Chairperson, CSI 2011; Dr. Narender O. Bansal, Org. Secretary, CSI 2011 Tel: 91 – 22 – 2649 0261/2649 4946, Fax: 91 – 22 – 2640 5920/2649 4946.
Email: csi2011@ymail.com, csimumbai2011@gmail.com Website: www.csi2011mumbai.com

Lecture on Buddism and Astronomy

By Prof. Trinh X. Thuan

UNESCO Kalinga Awardee, 2009; Prof. of Astronomy, University of Virginia, USA; UNESCO Kalinga Awardee for Popularisation of Science by UNESCO, Kalinga Chair awardee by Department of Science & Technology, Government of India.

Organised by Heart Care Foundation of India in association with Nehru Planetarium on behalf of RVPSP, Dept. of Science & Technology Govt.of India

At Nehru Planetarium Chankyapuri New Delhi on 27th Dec 2011 at 10.30 am

No fee, to register email to drkakroo@gmail.com, 9810301261

eMedinewS Events: Register at emedinews@gmail.com

3rd eMedinewS Revisiting 2011

The 3rd eMedinewS – revisiting 2011 conference will be held at Maulana Azad Medical College, New Delhi on Sunday January 22nd 2012.

The one–day conference will revisit and cover all the new advances in the year 2011. There will also be a webcast of the event. An eminent faculty is being invited to speak.

There will be no registration fee. Delegate bags, gifts, certificates, breakfast, lunch will be provided. The event will end with a live cultural evening, Doctor of the Year award, cocktails and dinner. Kindly register at www.emedinews.in

3rd eMedinewS Doctor of the Year Award

Dear Colleague, The Third eMedinews "Doctor of the Year Award" function will be held on 22nd January, 2012 at Maulana Azad Medical College at 5 pm. It will be a part of the entertainment programme being organized at the venue. If you have any medical doctor who you feel has made significance achievement in the year 2011, send his/her biodata: emedinews@gmail.com

3rd eMedinewS Revisiting 2011

Dr Ajay Kriplani (Surgical management of diabetes); Dr N K Bhatia ( What’s new in transfusion medicine); Dr Kaberi Banerjee (Fertility update); Dr Amit Bahrgava (Cancer update 2011), Onco Radiation update (Rajiv Gandhi Cancer Institute); Dr Ambrish Mithal (Vitamin D update), Dr Praveen Chandra (Interventional Cardiology update); Revisting 2011 (Dr K K Aggarwal), Portfolio management (Central Bank of India); Insurance update (LIC India); General Insurance (Doogar Associates)

    eMedinewS Special

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    Our Contributors

Dr Veena Aggarwal, Dr Arpan Gandhi, Dr Aru Handa, Dr Ashish Verma, Dr A K Gupta, Dr Brahm Vasudev, Dr GM Singh, Dr Jitendra Ingole, Dr Kaberi Banerjee (banerjee.kaberi@gmail.com), Dr Monica Vasudev, Dr MC Gupta, Dr Neelam Mohan (drneelam@yahoo.com), Dr Navin Dang, Dr Pawan Gupta(drpawangupta2006@yahoo.com), Dr Parveen Bhatia, (bhatiaglobal@gmail.com), Dr Prabha Sanghi, Dr Prachi Garg, Rajat Bhatnagar (http://www.isfdistribution.com), Dr. Rajiv Parakh, Dr Sudhir Gupta